4,5-DHP-DMT

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(Redirected from
1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole
)
4,5-DHP-DMT
Identifiers
  • 1-(2-Dimethylaminoethyl)-8,9-dihydropyrano[3,2-e]indole
JSmol)
  • CN(C)CCc1c[nH]c3ccc2OCCCc2c13
  • InChI=1S/C15H20N2O/c1-17(2)8-7-11-10-16-13-5-6-14-12(15(11)13)4-3-9-18-14/h5-6,10,16H,3-4,7-9H2,1-2H3 ☒N
  • Key:RMMYVKPVLLBYDW-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

1-(2-Dimethylaminoethyl)dihydropyrano(3,2-e)indole (4,5-DHP-DMT) is a tricyclic tryptamine derivative which acts as a potent and reasonably selective partial agonist for the serotonin receptor 5-HT2A, with a Ki of 17.0 nM, and moderate selectivity over related serotonin receptors. It has lower 5-HT2 affinity and efficacy than the related compound AL-37350A, but higher lipophilicity.[1][2]

See also

References

  1. PMID 1433172
    .
  2. PMID 12954071
    .
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