The season ended with Super Bowl XXVII when the Dallas Cowboys defeated the Buffalo Bills 52–17 at the Rose Bowl. This would be the third of the Bills’ four consecutive Super Bowl losses; as of 2021, no team has ever lost three OR four Super Bowls in a row (the earliest possible date that these figures could be matched would be either 2023 or 2024, and that would only happen if the Kansas City Chiefs--who lost Super Bowl LV in February 2020--lost in the Super Bowl for the next 2-3 seasons). Buffalo would join the Miami Dolphins of the early 1970s as the only team to reach three straight Super Bowls and not until the New England Patriots of the late 2010s would another team reach three in a row.
The NFL ceases to use the instant replay system that was in effect since the 1986 NFL season to review questionable on-field calls, due to many reviews taking up long periods of time. Instant replay would not return to the league until a more comprehensive instant replay review system with time limits was introduced in the 1999 NFL season.
To reduce injuries, any offensive player who is lined up in the backfield before the snap cannot chop block a defensive player who is already engaged above the waist by another offensive player.
Jerome Brown: A two-time All-Pro with the Philadelphia Eagles, Brown died on June 25, 1992, at the age of 27, following an automobile accident in Brooksville, in which both he and his 12-year-old nephew were killed when Brown lost control of his ZR1 Chevrolet Corvette at high speed and crashed into a palm tree. Brown was buried in his hometown of Brooksville.
Shane Curry: A selection of the Indianapolis Colts in the 1991 NFL Draft, Curry was shot and killed outside a Cincinnati nightclub during an argument over a blocked vehicle on May 4, 1992.
Mike Wise: Was a backup for the Raiders before being released after a fight instigated by a teammate, and had serious injuries which made it impossible for him to resume his career. Committed suicide at his home in California.
Thanksgiving: Two games were played on Thursday, November 26, featuring Houston at Detroit and the New York Giants at Dallas, with Houston and Dallas winning.
Week 16: The San Diego Chargers became the first (as of 2021 the only) team to start 0-4 and made the playoffs and they achieve that feat by beating The Los Angeles Raiders.
There was an unusual deviation between good teams and bad teams in the NFL in 1992. Only one team, the Denver Broncos; finished with eight wins and eight losses, nine teams had at least 11 wins, and eight teams had at least 11 losses. Only six teams had between seven, eight or nine wins in 1992.