2,5-Dimethoxy-4-ethoxyamphetamine

chemical classes. It was first synthesized by Alexander Shulgin.^[1] In his book PiHKAL, he lists the active dose range as 20–50 mg, and the duration as 10–14 hours.^[1] According to Shulgin, MEM produces color enhancement, visual phenomena, and pattern movement, among other effects.^[1]

affinity (K_i) for the 5-HT_2A (3,948 nM), 5-HT_2B (64.5 nM), 5-HT₇ (7,156 nM), and σ₁ (5,077 nM) receptors. It behaves as a partial agonist at the 5-HT_2A receptor.^[2] MEM is relatively selective for these sites and displays low/negligible (> 10,000 nM) affinity for a wide array of other targets.^[2]