2C-H

2C-H

Names
Preferred IUPAC name 2-(2,5-Dimethoxyphenyl)ethan-1-amine
Other names 2,5-Dimethoxy-phenethylamine
Identifiers
CAS Number	3600-86-0 (free base) Y 3166-74-3 (HCl) Y
3D model ( JSmol )	Interactive image
ChEMBL	ChEMBL287047 Y
ChemSpider	69096 Y
ECHA InfoCard	100.153.556
PubChem CID	76632
UNII	9A8XF4GA0X Y P2Y262S9PP (HCl) Y
CompTox Dashboard (EPA)	DTXSID80189564
InChI InChI=1S/C10H15NO2/c1-12-9-3-4-10(13-2)8(7-9)5-6-11/h3-4,7H,5-6,11H2,1-2H3 Y Key: WNCUVUUEJZEATP-UHFFFAOYSA-N Y InChI=1/C10H15NO2/c1-12-9-3-4-10(13-2)8(7-9)5-6-11/h3-4,7H,5-6,11H2,1-2H3 Key: WNCUVUUEJZEATP-UHFFFAOYAJ
SMILES O(c1ccc(OC)cc1CCN)C
Properties
Chemical formula	C10H15NO2
Molar mass	181.23 g/mol
Melting point	138 to 139 °C (280 to 282 °F; 411 to 412 K) (hydrochloride)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

2C-H (2,5-dimethoxyphenethylamine) is a lesser-known

History

2C-H was first synthesized in 1932 by Johannes S. Buck.^[1]

Use

2C-H is used as a precursor in the synthesis of other substituted phenethylamines such as 2C-B, 2C-I, and 2C-N.^[2] 2C-H has been found in trace amounts by the DEA's south central laboratory in tablets that were suspected of containing MDMA.^{[citation needed]}

Pharmacology

There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects.^[2] In the book PiHKAL, Alexander Shulgin lists both the dosage and duration of 2C-H effects as unknown.^[2] Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H.

Research

2C-H exhibits

As of October 31, 2016; 2C-H is a controlled substance (Schedule III) in Canada.[4]

United States

As of July 9, 2012, 2C-H is a

• Phenethylamine
• 2C (psychedelics)
• PiHKAL
• Psychedelics, dissociatives and deliriants

References