2C-T-16
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| Names | |
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| Preferred IUPAC name
2-{2,5-Dimethoxy-4-[(prop-2-en-1-yl)sulfanyl]phenyl}ethan-1-amine | |
| Identifiers | |
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3D model (
JSmol ) |
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| ChemSpider | |
PubChem CID
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| UNII | |
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| Properties | |
| C13H19NO2S | |
| Molar mass | 253.360 g/mol |
| Melting point | 193–194 °C (379–381 °F; 466–467 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2C-T-16 is a lesser-known
nitrostyrene intermediate, and did not complete the final synthetic step.[1] Synthesis of 2C-T-16 was finally achieved by Daniel Trachsel some years later,[2] and it was subsequently reported as showing similar psychedelic activity to related compounds, with a dose range of 10–25 mg and a duration of 4–6 hours,[3]: 788–789 making it around the same potency as the better-known saturated analogue 2C-T-7, but with a significantly shorter duration of action. Binding studies in vitro showed 2C-T-16 to have a binding affinity of 44 nM at 5-HT2A and 15 nM at 5-HT2C.[3]: 791 2C-T-16 and related derivatives are potent partial agonists of the 5-HT1A, 5-HT2A, 5-HT2B and 5-HT2C receptors and induce a head-twitch response in mice.[4]
Legality
Canada
As of October 31, 2016, 2C-T-16 is a controlled substance (Schedule III) in Canada.[5]
See also
- 2C-AL
- 2C-T-3
- 2C-T-28
- 3C-AL
- Phenethylamine
- Psychedelics, dissociatives and deliriants
References
- OCLC 25627628.
- .
- ^ ISBN 978-3-03788-700-4.
- S2CID 7135811.
- ^ "Canada Gazette – Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". 4 May 2016.
External links
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