2C-T-21

Source: Wikipedia, the free encyclopedia.

2C-T-21
Names
Preferred IUPAC name
2-{4-[(2-Fluoroethyl)sulfanyl]-2,5-dimethoxyphenyl}ethan-1-amine
Other names
4-(2-Fluoroethylthio)-2,5-dimethoxyphenethylamine
Identifiers
3D model (
JSmol
)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C12H18FNO2S/c1-15-10-8-12(17-6-4-13)11(16-2)7-9(10)3-5-14/h7-8H,3-6,14H2,1-2H3 checkY
    Key: ZBUUUKBTOCTOPW-UHFFFAOYSA-N checkY
  • InChI=1/C12H18FNO2S/c1-15-10-8-12(17-6-4-13)11(16-2)7-9(10)3-5-14/h7-8H,3-6,14H2,1-2H3
    Key: ZBUUUKBTOCTOPW-UHFFFAOYAH
  • COc1cc(SCCF)c(cc1CCN)OC
Properties
C12H18FNO2S
Molar mass 259.34 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

2C-T-21 (4-(2-fluoroethylthio)-2,5-dimethoxyphenethylamine) is a psychedelic phenethylamine of the 2C family sometimes used as an entheogen. It was first synthesized by Alexander Shulgin.

Dosage

In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as 8–12 mg.[1]

Effects

2C-T-21 is generally taken orally and effects typically last 7 to 10 hours.[1] The potential psychotherapeutic applications of this chemical were explored by Myron Stolaroff.[citation needed]

Pharmacology

The mechanism that produces 2C-T-21's hallucinogenic and entheogenic effects has not been established; however, it may result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

Dangers

On March 9, 2004, a 22-year-old

tonic-clonic seizure, and slipped into a coma. Four days later, on March 13, Downs died at Lane Memorial Hospital in Zachary, LA.[citation needed
]

This death became part of a two-year DEA investigation called

controlled substance analogues
and the death of James Edwards Downs. Little is known about the toxicity of 2C-T-21 beyond this incident.

Legality

2C-T-21 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-21 would probably be prosecuted under the

Federal Analog Act because of its structural similarities to 2C-T-7 and its known potential to cause death. In the wake of Operation Web Tryp
in July 2004, at least one distributor faced charges as a consequence of the death of James Downs from 2C-T-21 overdose.

Canada

As of October 31, 2016, 2C-T-21 is a controlled substance (Schedule III) in Canada.[3]

References

  1. ^ a b Alexander Shulgin. "2C-T-21". PiHKAL.
  2. ^ "News from DEA, News Releases, 07/22/04". Archived from the original on February 8, 2008.
  3. ^ Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)

External links

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