2CD-5EtO

2CD-5EtO

Identifiers
IUPAC name 1-(5-Ethoxy-2-methoxy-4-methylphenyl)-ethan-1-amine
JSmol)	Interactive image
SMILES CCOC1=CC(=C(C=C1C)OC)CCN
InChI InChI=1S/C12H19NO2/c1-4-15-11-8-10(5-6-13)12(14-3)7-9(11)2/h7-8H,4-6,13H2,1-3H3 Y Key:ZMQDQUPRBYFPSO-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

2CD-5EtO is a

of drugs, where either one or both of the methoxy groups at the 2,5-positions of the aromatic ring have been replaced by ethoxy. The term tweetio was derived phonetically from the sound of the "2-ETO" derivatives.

Many tweetio derivatives of various 2C drugs have been synthesized and tested, including the 2-ethoxy homologues 2CD-2EtO, 2CB-2EtO, 2CI-2EtO, 2CT-2EtO, 2CT2-2EtO, 2CT4-2EtO and 2CT7-2EtO, the 5-ethoxy homologues 2CD-5EtO, 2CE-5EtO, 2CB-5EtO, 2CT-5EtO and 2CT2-5EtO, and the 2,5-diethoxy homologues 2CD-diEtO, 2CB-diEtO and 2CT2-diEtO,^[1] as well as 2CE-5iPrO.^[2] In general, the 2-ethoxy homologues were all several times less potent and somewhat shorter acting than the parent compounds, while the 2,5-diethoxy homologues were far less potent and qualitatively milder even at high doses.^[3] The 5-ethoxy homologues however were of a similar potency to the parent compounds and much longer-lasting, with both 2CE-5EtO and 2CT2-5EtO lasting 24 hours or more.

References

External links

• 2C-D Entry in PiHKAL
• 2C-E Entry in PiHKAL
• 2C-T-2 Entry in PiHKAL