3',4'-Methylenedioxy-α-pyrrolidinobutiophenone
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3',4'-Methylenedioxy-α-pyrrolidinobutyrophenone (MDPBP) is a
cathinones, MDPBP has been shown to have reinforcing effects in rats.[6]
The main metabolic steps are thought to be demethylenation followed by methylation of one hydroxy group, aromatic and side chain hydroxylation, oxidation of the pyrrolidine ring to the corresponding lactam as well as ring opening to the corresponding carboxylic acid. CYP2C19 and CYP2D6 have been identified as the isoenzymes mainly responsible for demethylenation.[7]
Legal Status
As of October 2015[update] MDPBP is a controlled substance in Poland and China.[8]
See also
- α-Pyrrolidinobutiophenone (α-PBP)
- Butylone
- 3',4'-Methylenedioxy-α-pyrrolidinopropiophenone (MDPPP)
- Methylenedioxypyrovalerone (MDPV)
References
- ^ DE 1545591, Koeppe H, Zeile K, Ludwig G, "Verfahren zur Herstellung von α-Aminoketonen mit heterocyclischer Aminogruppe", published 28 May 1965, issued 7 August 1969, assigned to Boehringer Ingelheim
- PMID 24116392.
- PMID 21316166.
- PMID 27546909.
- PMID 21960541.
- PMID 28811192.
- PMID 24124065.
- ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.