3-hydroxyanthranilate oxidase
| 3-hydroxyanthranilate oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In
enzymology, a 3-hydroxyanthranilate oxidase (EC 1.10.3.5) (also called 3-HAO) is an enzyme that catalyzes the chemical reaction:[1]
- 3-hydroxyanthranilate + O2 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2
Thus, the two
3-hydroxyanthranilate and O2, whereas its two products are 6-imino-5-oxocyclohexa-1,3-dienecarboxylate and H2O2
.
This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with oxygen as acceptor. The systematic name of this enzyme class is 3-hydroxyanthranilate:oxygen oxidoreductase. This enzyme is also called 3-hydroxyanthranilic acid oxidase.
References
- PMID 23237916.
- Morgan LR Jr, Weimorts DM, Aubert CC (1965). "Oxidation Of 3-hydroxyanthranilic acid by a soluble liver fraction from poikilothermic vertebrates". Biochim. Biophys. Acta. 100: 393–402. PMID 14347936.
