4'-Methyl-α-pyrrolidinohexiophenone

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4'-Methyl-α-pyrrolidinohexiophenone
Clinical data
Other namesMPHP
Legal status
Legal status
Identifiers
  • (RS)-1-(4-Methylphenyl)-2-(1-pyrrolidinyl)-1-hexanone
JSmol)
ChiralityRacemic mixture
  • c2cc(C)ccc2C(=O)C(CCCC)N1CCCC1
  • InChI=1S/C17H25NO/c1-3-4-7-16(18-12-5-6-13-18)17(19)15-10-8-14(2)9-11-15/h8-11,16H,3-7,12-13H2,1-2H3
  • Key:YOSQVMGMENUCDX-UHFFFAOYSA-N

4'-Methyl-α-pyrrolidinohexiophenone (MPHP) is a

aryl, ketone and pyrrolidinyl groups are held constant, while the alkyl backbone can be varied anywhere between three and as many as seven carbons,[4] with highest potency usually seen with the pentyl or isohexyl backbone, and a variety of substituents are tolerated on the aromatic ring.[5]

In 2010 a group of researchers from the Institute of Forensic Medicine, University Hospital Jena, Germany concluded that MPHP can lead to serious poisoning with toxic liver damage and rhabdomyolysis.[6]

Legality

In the United States, MPHP is a

Schedule I Controlled Substance.[7] Sweden's public health agency suggested to classify MPHP as narcotic on June 1, 2015.[8]

See also

References

  1. PMID 12726846
    .
  2. PMID 19470220
    .
  3. PMID 21444164
    .
  4. ^ GB patent 1149366, "α-substituted-ketones and processes for their preparation." 
  5. PMID 16480278
    .
  6. PMID 21444164
    .
  7. ^ "Schedules of Controlled Substances: Temporary Placement of N-Ethylhexedrone, α-PHP, 4-MEAP, MPHP, PV8, and 4-Chloro-α-PVP in Schedule I". Drug Enforcement Administration. Archived from the original on 2021-04-30. Retrieved 2019-07-29.
  8. ^ "23 nya ämnen kan klassas som narkotika eller hälsofarlig vara". Retrieved 29 June 2015.
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