4-Amino-3-methyl-1-naphthol

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4-Amino-3-methyl-1-naphthol
Names
Preferred IUPAC name
4-Amino-3-methylnaphthalen-1-ol
Identifiers
3D model (
JSmol
)
ChemSpider
ECHA InfoCard
 100.001.360 Edit this at Wikidata
EC Number
  • 201-495-8
UNII
  • InChI=1S/C11H11NO/c1-7-6-10(13)8-4-2-3-5-9(8)11(7)12/h2-6,13H,12H2,1H3
    Key: YJRCNAAPGQBVFS-UHFFFAOYSA-N
  • CC1=C(C2=CC=CC=C2C(=C1)O)N
Properties
C11H11NO
Molar mass 173.215 g·mol−1
Appearance crystalline (HCl)[1]
Melting point 270 °C[1] HCl decays
HCl is soluble[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

4-amino-3-methyl-1-naphthol is a synthetic menadione analog. It is also known as vitamin K7,[1] and was named as such in 1950 when it was recognized as a compound with vitamin K activity.[2][3]

It can be made from

2-methylnaphthalene or menadione. It forms a crystalline hydrochloride salt (C11H11NO·HCl) from hydrochloric acid. At least 1 g of the salt dissolves in 25 ml of water at 75 °C. The salt turns pink to dark violet on exposure to air and light.[1]

4-Amino-3-methyl-1-naphthol or its hydrochloride have not been used as commercial medicinal forms of vitamin K unlike

phylloquinone and menadione for example.[4]

References

  1. ^
    ISBN 9781584881292
    .
  2. PMID 14782638
    .
  3. PMID 14847531
    .
  4. S2CID 975055
    .


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