4-Chloromethcathinone

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4-Chloromethcathinone
Legal status
Legal status
Identifiers
  • 1-(4-chlorophenyl)-2-(methylamino)-1-propanone
JSmol)
Melting point198 °C (388 °F)
  • ClC1=CC=C(C(C(C)NC)=O)C=C1
  • InChI=1S/C10H12ClNO/c1-7(12-2)10(13)8-3-5-9(11)6-4-8/h3-7,12H,1-2H3
  • Key:UEJBEYOXRNGPEI-UHFFFAOYSA-N

4-Chloromethcathinone (also known as 4-CMC and Clephedrone) is a stimulant drug of the cathinone class that has been sold online as a designer drug.[1][2][3]

The exact pharmacology of 4-CMC is unknown, though it is probably a dopamine and serotonin releasing agent. Its chemical structure closely resembles

para-chloromethamphetamine and studies involving mice indicate that it is neurotoxic.[4]

Legality

Clephedrone is an Anlage I controlled drug in Germany.

Sweden's public health agency suggested classifying 4-Chloromethcathinone (klefedron) as illegal narcotic on June 1, 2015.[5]

As of October 2015 4-CMC is a controlled substance in China.[6]

4-CMC is considered a Schedule 1 substance in Virginia.[7]

In December 2019, the

UNODC announced scheduling recommendations placing 4-CMC into Schedule II.[8]

See also

References

  1. ^ "4-Chloromethcathinone". Cayman Chemical. Retrieved 5 September 2015.
  2. PMID 25280452
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  5. ^ "23 nya ämnen kan klassas som narkotika eller hälsofarlig vara" [23 new substances can be classified as narcotic drugs or substances dangerous to health]. Folkhälsomyndigheten [The Public Health Authority] (in Swedish). 1 June 2015. Retrieved 5 September 2015.
  6. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" [Notice on Issuing the Measures for the Listing and Control of Non-Medicinal Narcotic Drugs and Psychotropic Substances] (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
  7. ^ "18VAC110-20-322. Placement of Chemicals in Schedule I." Commonwealth of Virginia. 2 December 2015. Retrieved 11 March 2016.
  8. ^ "World Health Organization recommends 12 NPS for scheduling". WHO. December 2019.