4-HO-DET

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4-HO-DET
Legal status
Legal status
Identifiers
  • 3-(2-Diethylaminoethyl)-1H-indol-4-ol
JSmol)
Melting point104 to 106 °C (219 to 223 °F)
  • CCN(CC)CCc1c[nH]c2cccc(O)c12
  • InChI=1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3 checkY
  • Key:OHHYMKDBKJPILO-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, is a

4-HO-DIPT.[1]

Analogs

4-HO-DET is the N,N-diethyl analog of psilocin. The acetic acid ester of 4-HO-DET is known as 4-AcO-DET and the phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin. These compounds may likely be prodrugs of 4-HO-DET as has been shown with the acetate and phospate esters of other methylated tryptamines such as psilocin.[2]

History

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosphoryloxy-analog ethocybin in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.[citation needed] It was later explored by Alexander Shulgin in his 1997 book TiHKAL.[3]

Dosage

TiHKAL reports moderate effects at 10–25 mg ingested orally.[4]

Effects

4-HO-DET produces psychedelic effects similar to LSD and psilocybin.[4]

Legality

United States

4-HO-DET is unscheduled in the United States, but purchase, sale, or possession for human consumption could be prosecuted under the Federal Analogue Act.[5]

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-HO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-hydroxi-N,N-diethyltryptamin (4-HO-DET), making it illegal to sell or possess.[6]

See also

References

  1. ISBN 978-0-12-819030-2
    .
  2. S2CID 32044725
    .
  3. OCLC 38503252
    .
  4. ^ a b Shulgin A, Shulgin A (September 1997). "#16 4-HO-DET". Isomer Design. Transform Press. Retrieved 28 November 2023.
  5. ^ "21 U.S. Code § 841 - Prohibited acts A", LII / Legal Information Institute, retrieved 2016-08-02
  6. ^ "Förordning om ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor;" [Ordinance amending the ordinance (1999: 58) on the prohibition of certain dangerous goods;] (PDF). Svensk författningssamling (Swedish Code of Statutes) (in Swedish). 6 October 2005. Archived from the original (PDF) on 26 June 2021. Retrieved 6 September 2013.

External links

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