4-HO-MiPT

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"Miprocin" redirects here. Not to be confused with Mupirocin.

4-HO-MiPT
isopropyl tryptamine
Routes of
administration		Oral, intranasal, rectal, IV, IM
ATC code
  • None
Legal status
Legal status
  • BR: Class F2 (Prohibited psychotropics)[1]
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
  • US: Unscheduled
Identifiers
  • 3-{2-[methyl(propan-2-yl)amino]ethyl}-1H-indol-4-ol
JSmol)
Melting point123 to 125 °C (253 to 257 °F)
  • CN(C(C)C)CCC2=CNC1=CC=CC(O)=C12
  • InChI=1S/C14H20N2O/c1-10(2)16(3)8-7-11-9-15-12-5-4-6-13(17)14(11)12/h4-6,9-10,15,17H,7-8H2,1-3H3 checkY
  • Key:RXKGHZCQFXXWFQ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

4-HO-MiPT (miprocin, 4-hydroxy-N-methyl-N-isopropyltryptamine) is a

magic mushrooms
.

History

4-HO-MiPT was presumably first synthesized by Alexander Shulgin. Its synthesis is described in his book TiHKAL along with reports by people who had ingested the compound. Shulgin's trials and other anecdotal information suggest that 4-HO-MiPT is a synthetic psychedelic similar in activity to psilocin. It is relatively uncommon and has only a short history of human use.

Chemistry

Miprocin is the 4-

4-HO-DMT
.

In August 2019, Chadeayne et al. solved the crystal structure of 4-HO-MiPT fumarate.[3] Its systematic name is [2-(4-hydroxy-1Hindol-3-yl)ethyl](methyl)propan-2-ylazanium 3-carboxyprop-2-enoate monohydrate. The salt consists of a protonated tryptammonium cation and a 3-carboxyacrylate (hydrogen fumarate) anion in the asymmetric unit along with a water molecule of crystallization.

Pharmacology

4-HO-MiPT is thought to be a

serotonin receptors.[2]

Toxicity

Very little is known about the toxicity of 4-HO-MiPT. Its chemical structure and pharmacological activity are very similar to psilocin, a compound which is not associated with compulsive use or physical dependence. However, because very little research has been done on 4-HO-MiPT, it cannot be definitively concluded that its pharmacological actions in the human body do not differ from those of psilocin. To date, there have been no reported deaths from 4-HO-MiPT.[citation needed]

Duration

Onset of action is 15 to 45 minutes and has a duration of 4 to 6 hours, depending on dose. The duration of action is one half-hour to two hours when injected IV.[citation needed]

Drug prohibition laws

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-HO-MiPT as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of 1 November 2005, in regulation SFS 2005:733 listed as "4-hydroxi-N,N-metylisopropyltryptamin (4-HO-MIPT)", making it illegal to sell or possess.[4]

United Kingdom

The substance could also be considered illegal in the UK under the Misuse of Drugs Act 1971.

United States

4-HO-MiPT is an unscheduled drug in the United States. However, it is arguably an

Federal Analog Act
.

Russia

4-HO-MiPT is in Schedule 1 in Russia as an analog of 4-hydroxytryptamine.

See also

References

  1. ^ Anvisa (24 July 2023). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 25 July 2023). Archived from the original on 27 August 2023. Retrieved 27 August 2023.
  2. ^ a b c "4-HO-MiPT". Psychedelic Science Review. 6 January 2020. Retrieved 5 July 2022.
  3. PMID 31523457
    .
  4. ^ "Förordning om ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor" [Regulation amending the Ordinance (1999: 58) on Prohibition against certain dangerous goods] (PDF). Swedish Code of Statutes (in Swedish). 6 October 2005. Archived from the original (PDF) on 26 June 2021. Retrieved 6 September 2013.

External links

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