ASAH2C

Neutral ceramidase C also known as N-acylsphingosine amidohydrolase 2C or non-lysosomal ceramidase C or ASAH2C is a ceramidase enzyme which in humans is encoded by the ASAH2C gene.^[2]

References

Further reading

• Choi MS, Anderson MA, Zhang Z, Zimonjic DB, Popescu N, Mukherjee AB (October 2003). "Neutral ceramidase gene: role in regulating ceramide-induced apoptosis". Gene. 315: 113–22.
  PMID 14557071
  .
• El Bawab S, Roddy P, Qian T, Bielawska A, Lemasters JJ, Hannun YA (July 2000). "Molecular cloning and characterization of a human mitochondrial ceramidase". The Journal of Biological Chemistry. 275 (28): 21508–13.
  PMID 10781606
  .
• Tani M, Sano T, Ito M, Igarashi Y (November 2005). "Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets". Journal of Lipid Research. 46 (11): 2458–67.
  PMID 16061940
  .
• Galadari S, Wu BX, Mao C, Roddy P, El Bawab S, Hannun YA (February 2006). "Identification of a novel amidase motif in neutral ceramidase". The Biochemical Journal. 393 (Pt 3): 687–95.
  PMID 16229686
  .
• Hwang YH, Tani M, Nakagawa T, Okino N, Ito M (May 2005). "Subcellular localization of human neutral ceramidase expressed in HEK293 cells". Biochemical and Biophysical Research Communications. 331 (1): 37–42.
  PMID 15845354
  .
• Osawa Y, Uchinami H, Bielawski J, Schwabe RF, Hannun YA, Brenner DA (July 2005). "Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha". The Journal of Biological Chemistry. 280 (30): 27879–87.
  PMID 15946935
  .

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