AT-076

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AT-076
Identifiers
  • (3R)-7-hydroxy-N-[(2S)-1-[4-(3-hydroxyphenyl)piperidin-1-yl]-3-methylbutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
JSmol)
  • CC(C)[C@@H](CN1CCC(CC1)C2=CC(=CC=C2)O)NC(=O)[C@H]3CC4=C(CN3)C=C(C=C4)O
  • InChI=1S/C26H35N3O3/c1-17(2)25(16-29-10-8-18(9-11-29)19-4-3-5-22(30)12-19)28-26(32)24-14-20-6-7-23(31)13-21(20)15-27-24/h3-7,12-13,17-18,24-25,27,30-31H,8-11,14-16H2,1-2H3,(H,28,32)/t24-,25-/m1/s1
  • Key:LGYDWJJZDCXEOV-JWQCQUIFSA-N

AT-076 is a so-called

affinity for the nociceptin receptor by 10-fold and for the μ- and δ-opioid receptors by 3-6-fold.[1]

See also

References

  1. ^
    PMID 25635572
    .


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