Acenocoumarol
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| Clinical data | |
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| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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| Routes of administration | Oral |
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| Pharmacokinetic data | |
| Metabolism | Hepatic |
| Elimination half-life | 8 to 11 hours |
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JSmol) | |
| Chirality | Racemic mixture |
| Melting point | 196 to 199 °C (385 to 390 °F) |
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Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is generic, so is marketed under many brand names worldwide.[1]
References
- ^ "International listings for acenocoumarol". Drugs.com.
Further reading
- Cesar JM, García-Avello A, Navarro JL, Herraez MV (October 2004). "Aging and oral anticoagulant therapy using acenocoumarol". Blood Coagulation & Fibrinolysis. 15 (8): 673–676. S2CID 19214006.
- Lengyel M (December 2004). "[Warfarin or acenocoumarol is better in the anticoagulant treatment of chronic atrial fibrillation?]". Orvosi Hetilap. 145 (52): 2619–2621. PMID 15724697.
- Ufer M (2005). "Comparative pharmacokinetics of vitamin K antagonists: warfarin, phenprocoumon and acenocoumarol". Clinical Pharmacokinetics. 44 (12): 1227–1246. S2CID 42970169.
- Montes R, Ruiz de Gaona E, Martínez-González MA, Alberca I, Hermida J (April 2006). "The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients". British Journal of Haematology. 133 (2): 183–187. S2CID 369821.
External links
- Diseases Database (DDB): 29202