Agnes Ullmann

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Agnes Ullmann
Born(1927-04-14)14 April 1927
Institut Pasteur

Agnes Ullmann (14 April 1927[1] – 25 February 2019) was a French microbiologist.

Biography

Ullmann received her doctorate in microbiology from the

Institut Pasteur in 1958/59 working with Jacques Monod, she moved to France in 1960 with the support of Monod, who smuggled her and her husband over the Austria/Hungary border in a Hungarian caravan.[2][3]
With a grant from the Rockefeller Foundation she went to the laboratory of Monod at the Institut Pasteur, where she remained for the rest of her career. There she became a professor, laboratory director and in 1982 a member of the Board of Directors.

Ullmann initially dealt with the effects of antibiotics at the Institut Pasteur and was able to elucidate, among other things, the mode of action of

E. coli
. Later, she discovered another factor that boosts catabolite repression (catabolite modulator factor, or CMF).

Ullmann subsequently dealt with the mode of action of the whooping cough pathogen and its toxin. She showed that the toxin increases the cAMP production in the host cell and thus disturbs their metabolism. The ability of the toxin to provide other molecules with access to the attacked host cell also helped her to develop vaccines by coupling the genetically engineered whooping cough toxin with antigenic fragments that were to be immunized against.[5]

In 2002 she received the

Robert Koch Medal. She was an honorary member of the Hungarian Academy of Sciences and of the European Academy of Microbiology (EAM). EAM President Philippe Sansonetti recalled all her contributions to microbiology in the "I n memoriam Agnes Ullmann" [6]

In 1978, with

André Lwoff, she published a collection of essays by Jacques Monod[7] and she published two anthologies in memory of him.[8][9]

Ullmann became a French citizen in 1966.[5]

Works

External links

See also

References

  1. ^ "ISNI 0000000066423234 Agnes Ullmann (born 1928 - died February 25, 2019, Paris 16e (France))". ISNI. 15 December 1986. Retrieved 14 October 2018.
  2. ^ "The Main Characters". Sean B. Carroll. Retrieved 16 October 2018. A blog post by Sean B. Carroll about his book on Monod, Brave Genius, with photo from Ullmann
  3. PMID 22994486
    .
  4. ^ "Ullmann, Multiple action of cAMP: from gene regulation to bacterial virulence, Robert Koch Foundation Lecture on the occasion of the Koch Medal 2002". Archived from the original on 3 October 2003.
  5. ^ a b Kurth 2002.
  6. ^ "Ullman Agnes". Hungarian Academy of Sciences (in Hungarian). Retrieved 16 October 2018.
  7. ^ Ullman and Lwoff (eds.) 2003.
  8. ^ Quagliariello, Bernardi, and Ullmann (eds.) 1987.
  9. ^ Ullman (ed.) 1986.
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