Akiko Iwasaki

Source: Wikipedia, the free encyclopedia.
Akiko Iwasaki
岩崎明子
Born (1970-09-13) September 13, 1970 (age 53)
NationalityAmerican
EducationUniversity of Toronto, National Institutes of Health
Spouse
Developmental Biology
InstitutionsYale University, Howard Hughes Medical Institute
External videos
video icon "Long Covid: A parallel pandemic", Akiko Iwasaki and others, Knowable Magazine, August 8, 2022.

Akiko Iwasaki (岩崎明子, Iwasaki Akiko, born September 13, 1970) is a

commensal bacteria, COVID-19 and Long COVID
.

Iwasaki was elected to the National Academy of Sciences in 2018.[3] She is the 2023–2024 president of the American Association of Immunologists.[4]

Biography

Iwasaki was born and raised in Iga, Japan by her father Hiroshi, a physicist, and mother Fumiko, who fought for women's rights in the workplace.[5] She has two sisters.[5] After high school she moved to Toronto, Canada, where in 1994, she received her bachelor's degree in biochemistry and physics from the University of Toronto. She had hopes of becoming a mathematician or physicist like her father. However, her interests changed after taking an immunology class.[2]

Iwasaki earned her doctoral degree in immunology from the University of Toronto in 1998. Iwasaki did her postdoctoral fellow at the National Institutes of Health in the lab of mucosal immunologist Brian Lee Kelsall.[5] In 2000, she started her own lab at Yale University.[2] In 2022, Iwasaki was awarded a Sterling Professorship, the highest academic honor professors receive at Yale University.[6]

Major contributions

Herpes simplex virions, TEM. Herpes simplex virus is one of the many viruses Iwasaki studies.
DNA vaccination
elicit an immune response.

While working on her PhD project of how

antigens, coded for by the vaccines because the DNA vaccines work best when injected into the muscle.[2]

Iwasaki's research continues to focus on understanding

microbiocides for the prevention of transmission of viral and bacterial pathogens.[7] Iwasaki has developed a two-stage vaccination strategy called "prime and pull" that involves a conventional vaccine as a first step and then application of chemokines to the target tissue as a second step.[5] Based on this strategy, Iwasaki has developed a vaccine that is currently in a clinical trial to treat women with precancerous lesions in the cervix to prevent cervical cancer.[5] Serving on Yale University's Science Strategy Committee, Iwasaki has advocated for harnessing the beneficial aspects of inflammation to "combat widespread diseases like stroke, heart disease, and diabetes".[8]

Building on her interests in immune responses to viral infection, Iwasaki has also led research into

SARS-CoV-2 infection.[9][10][11] She is also examining the effects of Long COVID and other syndromes that occur following acute infections.[12]

According to Google Scholar, one of her publications, "Toll-like receptor control of the adaptive immune response,"[13] has been cited over 5,300 times as of August 2023 and was published in Nature Immunology in October 2004.[14] In January 2015, one of Iwasaki's studies was published in the Proceedings of the National Academy of Sciences.[7] The study, "Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells", investigates the relationship between temperature and immune responses.[15]

Personal life

Iwasaki is well known as an advocate for women in science, including voicing support for affordable childcare.[9][16][17] Additionally, she has spoken out in support of immigrants and their contributions to science.[18] Iwasaki has gained a following on Twitter for her public health advice about COVID-19, advocating for social distancing early in the pandemic.[19][20][21]

She is married to

immunobiology at Yale School of Medicine. They have two daughters.[22][23]

Honors

Publications

References

  1. ^ Zhang, Brian (2022-03-02). "Akiko Iwasaki named Sterling Professor". Yale Daily News. Retrieved 2022-03-07.
  2. ^ a b c d "Akiko Iwasaki, PhD". Howard Hughes Medical Institute Our Scientists. Howard Hughes Medical Institute. Retrieved 4 May 2015.
  3. ^ "Six Yale professors elected to National Academy of Sciences". yale.edu. May 1, 2018. Retrieved December 28, 2020.
  4. ^ "2023 AAI Election". The American Association of Immunologists. Retrieved May 24, 2023.
  5. ^
    PMID 30509976
    .
  6. ^ a b "Iwasaki Is Named a Sterling Professor". medicine.yale.edu. Retrieved 2022-02-25.
  7. ^ a b c d e f g h "Akiko Iwasaki PhD". Yale University Biological & Biomedical Sciences. Yale University. Retrieved 4 May 2015.
  8. ^ Belli, Brita (2018-11-14). "At alumni assembly, leading faculty address Yale's future in the sciences". YaleNews. Retrieved 2020-07-12.
  9. ^ a b "COVID-19 Research: Women Are Changing the Face of the Pandemic". GEN - Genetic Engineering and Biotechnology News. 2020-07-06. Retrieved 2020-07-12.
  10. ^ Forman, Robert. "Gift from Ludwig Family Foundation Funds Urgent COVID Research by School of Medicine Scientists". Yale School of Medicine. Retrieved 2020-07-12.
  11. ^ "Why Men May Fare Worse than Women Against SARS-CoV-2". HHMI.org. Retrieved 2020-07-12.
  12. ^ "Akiko Iwasaki, PhD, on the latest long COVID-19 research". American Medical Association. April 11, 2022. Retrieved 10 August 2022.
  13. ^ Iwasaki, Akiko. "Toll-like receptor control of the adaptive immune response" (PDF). Nature Immunology. Nature Publishing Group. Archived from the original (PDF) on 18 May 2015. Retrieved 4 May 2015.
  14. ^ "Google Scholar". scholar.google.com. Retrieved 2020-07-12.
  15. ^ "Cold virus replicates better at cooler temperatures". ScienceDaily. Retrieved 2020-07-12.
  16. ^ Kristoffersen, Matt (February 25, 2020). "Postdocs struggle with child care costs". yaledailynews.com. Retrieved 2020-07-12.
  17. ^ Kristoffersen, Matt; Lyng-Olsen, Helena (October 14, 2019). "Professors question gender inequity of Nobel laureates". yaledailynews.com. Retrieved 2020-07-12.
  18. ^ "Scientists and Societies Decry Trump Executive Order on Immigration Visas". GEN - Genetic Engineering and Biotechnology News. 2020-06-25. Retrieved 2020-07-12.
  19. ^ Belli, Brita (2020-03-16). "Amid coronavirus crisis, Yale scientists find useful tool in Twitter". YaleNews. Retrieved 2020-07-12.
  20. ^ Kaufman, Mark (24 April 2020). "Who to follow on Twitter for legit, trustworthy coronavirus info". Mashable. Retrieved 2020-07-12.
  21. ^ Kaufman, Mark (12 March 2020). "We have a potent weapon against coronavirus. We should use it". Mashable. Retrieved 2020-07-12.
  22. ^ "Heeding the call of basic research". Yale School of Medicine. Retrieved 2020-09-12.
  23. ^ "Profile: Akiko Iwasaki". British Society of Immunology. Archived from the original on 2021-06-24. Retrieved 2020-09-12.
  24. ^ "2019 Seymour & Vivian Milstein Award for Excellence in Interferon and Cytokine Research". International Cytokine & Interferon Society. 2019-04-22. Retrieved 2019-04-23.
  25. ^ "New Members". American Academy of Arts & Sciences. Retrieved 2021-04-24.
  26. ^ Meislin, Margy (2022-06-22). "Lupus Research Alliance Awards 2022 Lupus Insight Prize to Immunologist Dr. Akiko Iwasaki: Renowned immunology expert honored". Lupus Research. Retrieved 2024-02-22.
  27. ^ "Else Kröner Fresenius Prize for Medical Research 2023". Else Kröner-Fresenius-Stiftung. Retrieved 2023-05-08.
  28. ^ Meislin, Margy (2024-01-30). "Lupus Research Alliance 2023 Dr. William E. Paul Distinguished Innovator Award Granted to Yale School of Medicine Researcher Akiko Iwasaki, Ph.D." Lupus Research. Retrieved 2024-02-22.