Allolactose

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Allolactose
Skeletal formula of allolactose
Ball-and-stick model of the allolactose molecule
Names
IUPAC name
6-O-β-D-Galactopyranosyl-D-glucopyranose
Systematic IUPAC name
(3R,4S,5S,6R)-6-[[(2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxane-2,3,4,5-tetrol
Other names
6-O-β-D-Galactopyranosyl-D-glucose; β-D-Galactopyranosyl (1→6)-D-glucose
Identifiers
3D model (
JSmol
)
ChEBI
ChemSpider
UNII
  • InChI=1S/C12H22O11/c13-1-3-5(14)8(17)10(19)12(23-3)21-2-4-6(15)7(16)9(18)11(20)22-4/h3-20H,1-2H2/t3-,4-,5+,6-,7+,8+,9-,10-,11?,12-/m1/s1 checkY
    Key: DLRVVLDZNNYCBX-VDGMBKLFSA-N checkY
  • InChI=1/C12H22O11/c13-1-3-5(14)8(17)10(19)12(23-3)21-2-4-6(15)7(16)9(18)11(20)22-4/h3-20H,1-2H2/t3-,4-,5+,6-,7+,8+,9-,10-,11?,12-/m1/s1
    Key: DLRVVLDZNNYCBX-VDGMBKLFBT
  • O[C@H]1[C@H](O)[C@H](OC(O)[C@@H]1O)CO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O
Properties
C12H22O11
Molar mass 342.296 g/mol
Density 1.768 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Allolactose is a

β-galactosidase
.

It is an

enteric bacteria. It binds to a subunit of the tetrameric lac repressor, which results in conformational changes and reduces the binding affinity of the lac repressor to the lac operator, thereby dissociating it from the lac operator. The absence of the repressor allows the transcription of the lac operon to proceed. A non-hydrolyzable analog of allolactose, isopropyl β-D-1-thiogalactopyranoside
(IPTG), is normally used in molecular biology to induce the lac operon.

See also

External links