Alopecia mucinosa
Alopecia mucinosa | |
---|---|
Other names | Follicular mucinosis |
Specialty | Dermatology |
Alopecia mucinosa, also known as Follicular mucinosis, Mucinosis follicularis, Pinkus' follicular mucinosis, and Pinkus' follicular mucinosis–benign primary form, is a
Alopecia mucinosa is divided into three different variants, primary acute, primary chronic, and secondary alopecia mucinosa.[5]
Signs and symptoms
Follicle
Causes
Although the precise pathophysiology is uncertain, it has been suggested that cell-mediated immunity and circulating immune complexes play a part in responding to persistent antigens like Staphylococcus aureus.[7]
Diagnosis
Alopecia mucinosa patients require many skin biopsy samples for examination. Alopecia mucinosa is characterized by follicular degeneration and a buildup of mucin inside the follicles.[6]
Classification
The primary acute form of alopecia mucinosa is more common in children and young adults, characterized by isolated lesions on the scalp and skull that go away on their own in a short amount of time. The primary chronic variant of alopecia mucinosa is more common in slightly older age groups, has many disseminated lesions, and has a longer course with recurrent recurrences after treatment. A variety of benign and malignant illnesses can lead to secondary alopecia mucinosa.[5]
Treatment
Topical, intralesional, and systemic
See also
- List of cutaneous conditions
References
- ISBN 0-07-138076-0.
- ISBN 0-7216-2921-0.
- ISBN 978-1-4160-2999-1.
- PMID 19624994.
- ^ PMID 31363428.
- ^ a b Gerstner, Gervaise L (2022-03-16). "Alopecia Mucinosa (Follicular Mucinosis) Clinical Presentation: Physical Examination". Medscape Reference. Retrieved 2024-03-07.
- PMID 24350019.
- PMID 15748592.
Further reading
- Rongioletti, Franco; De Lucchi, Simona; Meyes, Dan; Mora, Marco; Rebora, Alfredo; Zupo, Simonetta; Cerruti, Giannamaria; Patterson, James W. (2009-11-24). "Follicular mucinosis: a clinicopathologic, histochemical, immunohistochemical and molecular study comparing the primary benign form and the mycosis fungoides-associated follicular mucinosis". Journal of Cutaneous Pathology. 37 (1). Wiley: 15–19. PMID 19615011.
- Zvulunov, Alex; Shkalim, Vered; Ben-Amitai, Dan; Feinmesser, Meora (2012). "Clinical and histopathologic spectrum of alopecia mucinosa/follicular mucinosis and its natural history in children". Journal of the American Academy of Dermatology. 67 (6). Elsevier BV: 1174–1181. PMID 22579407.