Angiostrongylus costaricensis

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Angiostrongylus costaricensis
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Animalia
Phylum: Nematoda
Class: Chromadorea
Order: Rhabditida
Family: Angiostrongylidae
Genus: Angiostrongylus
Species:
A. costaricensis
Binomial name
Angiostrongylus costaricensis
Morera & Céspedes, 1971[1]

Angiostrongylus costaricensis is a species of parasitic nematode and is the causative agent of abdominal angiostrongyliasis in humans.[1] It occurs in Latin America and the Caribbean.[2][3]

Hosts

Rodents are the normal definitive hosts, especially the

mollusc tissue (e.g. undercooked or raw snails or accidentally on produce) or possibly food contaminated with slime containing such larvae.[3]

Molluscs
are the intermediate host and are infected through ingestion or penetration of the foot by L1 infective larvae from infected feces.

Pathology

Pathology is due to both the adults and the eggs. Adults in the ileo-caecal arterioles cause an inflammatory (eosinophilic) response in humans. In the Cotton Rat the adult worms cause local haemorrhages.[citation needed]

The intestinal wall is also affected. In humans there is a thickening of the intestinal wall (ileum, appendix and caecum). In rats with heavy infestations there is a yellow discolouring of the surface of the intestinal walls.[citation needed]

Clinical signs and diagnosis

  • Abdominal pain which presents as a palpable mass on clinical examination
  • Anorexia
  • Diarrhoea
  • Vomiting

In the blood and tissue biopsy there is

enzyme-linked immunosorbent assays
(ELISA).

This is a rare disease. In Martinique, a French island of the Antilles, two confirmed cases and two probable cases were identified during an 18-year period (2000-2017), with an estimated incidence of 0.2 cases per year (0.003 case/year/100.000 inhabitants).[4]

Diagnosis

Diagnosis is based primarily on detection of worms and/or eggs in biopsy specimens.[3]

References

  1. ^ a b Morera, P., & Céspedes, R. (1971). Angiostrongylus costaricensis n. sp.(Nematoda: Metastrongyloidea), a new lungworm occurring in man in Costa Rica. Revista de Biología Tropical, 18(1-2), 173-185. PDF Open access icon
  2. ^
    PMID 8107609
    .
  3. ^ a b c d e "CDC - DPDx - Angiostrongylus costaricensis". www.cdc.gov. 2019-06-19. Retrieved 2019-08-14.
  4. PMID 29633710. Open access icon