Hypohidrosis
Hypohidrosis. | |
---|---|
Specialty | Dermatology, neurology |
Prognosis | hyperthermia, heat stroke and death |
Hypohidrosis is a disorder in which a person exhibits diminished sweating in response to appropriate stimuli. In contrast with
Causes
The causes are the following:[citation needed]
- Anticholinergic agents
- Opioids
- Botulinum toxin
- Alpha-2 receptor antagonists
- Clonidine
- Barbiturates
- Zonisamide
- Topiramate
Physical agents
Dermatological
- X-linked hypohidrotic ectodermal dysplasia
- Incontinentia pigmenti
- Bazex disease
- Ectodermal dysplasia
- Fabry disease
- Miliaria
- Sjögren syndrome
- Systemic sclerosis
- Graft-versus-host disease
Neuropathic
- Ectodermal dysplasia
- Multiple system atrophy
- Dementia with Lewy bodies
- Multiple sclerosis
- Cerebrovascular accident
- Tumour
- Encephalitis
- Cervical myelopathy
- Diabetes mellitus
- Guillain–Barré syndrome
- Hereditary sensory and autonomic neuropathy
- Alcoholism
- Amyloidosis
- Ross syndrome
- Pure autonomic failure
- Horner's syndrome
- ROSAH syndrome
Diagnosis
Sweat is readily visualized by a topical indicator such as iodinated starch (Minor test) or sodium alizarin sulphonate, both of which undergo a dramatic colour change when moistened by sweat. A thermoregulatory sweat test can evaluate the body’s response to a thermal stimulus by inducing sweating through a hot box ⁄ room, thermal blanket or exercise. Failure of the topical indicator to undergo a colour change during thermoregulatory sweat testing indicates hypohidrosis, and further tests may be required to localize the lesion.[citation needed]
Magnetic resonance imaging of the brain and ⁄ or spinal cord is the best modality for evaluation when the lesion is suspected to be localized to the central nervous system.[citation needed]
Management
The treatment options for hypohidrosis and anhidrosis are limited. Those with hypohidrosis should avoid drugs that can aggravate the condition (see "Medications", under
Citations
- S2CID 206038609.