Anisocytosis
| Anisocytosis | |
|---|---|
 | |
| Human red blood cells from a case of anisocytosis. |
Anisocytosis is a medical term meaning that a patient's
giant platelets
or platelet clumps. In addition, it is a characteristic feature of bovine blood.
The
red cell distribution width (RDW) is a measurement of anisocytosis[1] and is calculated as a coefficient of variation of the distribution of RBC volumes divided by the mean corpuscular volume (MCV
).
Types
Anisocytosis is identified by RDW and is classified according to the size of RBC measured by MCV. According to this, it can be divided into
- Anisocytosis with sickle cell anemia
- Anisocytosis with macrocytosis – Folate or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome
Increased RDW is seen in
iron deficiency anemia and decreased or normal in thalassemia
major (Cooley's anemia), thalassemia intermedia
- Anisocytosis with normal RBC size – Early iron, vit B12 or folate deficiency, dimorphic anemia, Sickle cell disease, chronic liver disease, myelodysplastic syndrome[2]
Etymology
From Ancient Greek: an- without, or negative quality, iso- equal, cyt- cell, -osis condition.[3]
See also
References
- ISBN 978-1-4051-4265-6. Retrieved 10 November 2010.
- ^ Red Cell Distribution Width (RDW) at eMedicine
- ^ "Archived copy" (PDF). Archived from the original (PDF) on 2018-08-20. Retrieved 2018-05-19.
{{cite web}}: CS1 maint: archived copy as title (link)
External links
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