Anne Warner (scientist)
Anne Warner | |
---|---|
Born | Anne Elizabeth Brooks 25 August 1940 |
Died | 16 May 2012 | (aged 71)
Nationality | English |
Alma mater | University of London (PhD) |
Scientific career | |
Fields | Electrophysiology |
Institutions | University College London |
Thesis | The effect of pH on the membrane conductance of skeletal muscle (1964) |
Doctoral advisor | Otto Hutter |
Anne E. Warner
Education
Born Anne Elizabeth Brookes on 25 August 1940 at
Research
Warner was a participant and leader in a wide variety of research projects, and is best known for her work into the role of
To prove the essential role of these gap junctions in embryological development, Warner conducted experiments during the 1980s to block these junctions and observe the resulting effects.[11] Using the 8-cell-embryos of the African clawed frog, Xenopus,[14][15] she used antibody injections to block the channels in the connections of the gap junctions. After injecting the embryos with a specific antibody, which was said to have blocked the channels of gap junctions, Warner confirmed the blockage of the channels by injecting dyes into the cells in addition to confirming the lack of electrical coupling that she observed in earlier experiments.[11]
After confirming the successful blocking of the gap junctions in the 8-cell-embryos, Warner continued to grow the embryos and took note that due to the blockage of the gap junctions, development of the toads was abnormal.[11] Thus, Warner was the scientist responsible for confirming the crucial role of gap junction in the successful and normal development of cells from embryos to mature organisms. Through this discovery, Warner contributed to the growing research on the process of cell proliferation and maturation from an embryo to a fully functioning organism.
Career
In addition to her research, Warner was involved in many scientific organisations, often in a leadership role.[
Personal life
Warner met her husband Michael while they were both members of the stage crew at University College London. Her husband predeceased her by a few weeks.
Her health declined after a
References
- ^ "Notices 2012". Royal Society. Archived from the original on 12 October 2012.
- ^ "Prof Anne Warner". Archived from the original on 17 December 2010. Retrieved 23 May 2012.
- ^ "Listening in on cells' channels of communication". New Scientist. 17 November 1977.
- ^ a b c d e f g Ashmore, Jonathan (2012). "Anne Warner FRS 1940–2012". The Guardian.
- PMID 10207898.
- PMID 1320432.
- PMID 2458367.
- ^ "Anne Warner's UCL page". Archived from the original on 12 March 2008.
- Physiological Society. Archived from the original(PDF) on 8 May 2018. Retrieved 29 May 2012.
- ^ doi:10.1093/ref:odnb/105357. (Subscription or UK public library membershiprequired.)
- ^ a b c d e "How cells seal each other's fates". New Scientist. 11 October 1984. p. 16.
- PMID 6040154.
- S2CID 4188170.
- S2CID 4245621.
- S2CID 4245611.
- .
- ^ "My Friend Anne". blog.prof.so. Archived from the original on 21 November 2016. Retrieved 20 November 2016.