Left anterior descending artery

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(Redirected from
Anterior interventricular branch of left coronary artery
)
Left anterior descending artery
left ventricle (LV)
Identifiers
Latinramus interventricularis anterior arteriae coronariae sinistrae
Acronym(s)LAD
TA98A12.2.03.202
TA24143
FMA3862
Anatomical terminology]

The left anterior descending artery (also LAD, anterior interventricular branch of left coronary artery, or anterior descending branch) is a branch of the

left ventricle.[1] It provides about half of the arterial supply to the left ventricle and is thus considered the most important vessel supplying the left ventricle.[citation needed] Blockage of this artery is often called the widow-maker infarction due to a high risk of death.[2]

Structure

Course

It first passes at posterior to the

]

Although rare, multiple anomalous courses of the LAD have been described. These include the origin of the artery from the right aortic sinus.[3]

Branches

The LAD gives off two types of branches: septals and diagonals.

  • Septals originate from the LAD at 90 degrees to the surface of the heart, perforating and supplying the anterior 2/3 of the interventricular septum.
  • Diagonals run along the surface of the heart and supply the lateral wall of the
    left ventricle and the anterolateral papillary muscle
    .

Segments

Function

The artery supplies the anterior region of the left ventricle, including: the anterolateral

left ventricle and is therefore considered the most critical vessel in terms of myocardial blood supply.[citation needed
]

Left: Critical stenosis (95%) of the proximal LAD in a patient with Wellens' Warning.
Right: The same patient after reperfusion.

Widow maker

Widow maker is an alternative name for the anterior interventricular branch of the left coronary artery.[8][2] The name widow maker may also apply to the left coronary artery[9] or severe occlusions to that artery.[10][11]

This term is used because the left main coronary and/or the left anterior descending supply blood to large areas of the heart. This means that if these arteries are abruptly and completely occluded it will cause a massive

platelets streaming to the site of a ruptured cholesterol plaque. Even a small amount of plaque in this area can (for a variety of poorly understood reasons) rupture and cause death; bypassing chronic blockages or trying to open them up with angioplasty does not prevent heart attack but it can restore blood flow in case of a sudden blockage or heart attack and if performed within a rapid time period can minimize the damage done. An example of the devastating results of a complete occlusion of the LAD artery was the sudden death of former NBC News Washington Bureau Chief Tim Russert,[12] as well as the near-death of film director Kevin Smith.[13]

From the minute a widow maker heart attack hits, survival time ranges from minutes to several hours. Rapidly progressing symptoms should signal the need for immediate attention. Symptoms of initial onset may include nausea, shortness of breath, pain in the head, jaw, arms or chest, numbness in fingers, often of a novel but imprecise sensation which builds with irregular heart beat. Early symptoms may be mistaken for food poisoning, flu or general malaise until they intensify. A widow maker cannot kill instantly but induces cardiac arrest which may do so within 10 to 20 minutes of no circulation. A victim with no pulse or breath is still alive, living off oxygen stored in the blood and may be able to be rescued if treatment is begun promptly within this window.[14]

Additional images

  • Coronary arteries (labeled in red text)
    Coronary arteries (labeled in red text)
  • The arch of the aorta, and its branches.
    The arch of the aorta, and its branches.
  • Heart attack
    Heart attack
  • Cardiac vessels
    Cardiac vessels
  • Human heart with coronary arteries
    Human heart with coronary arteries
  • Heart coronary territories
    Heart coronary territories

References

Public domain This article incorporates text in the public domain from page 547 of the 20th edition of Gray's Anatomy (1918)

External links