Anti-actin antibodies
Anti-actin antibodies (AAA)[1] are found at increased frequency in certain autoimmune diseases and may be of some diagnostic value.
In coeliac disease, anti-actin antibody levels correlate with the level of intestinal damage.[2][3]
In autoimmune hepatitis, anti-actin antibody levels correlate with patterns of immune recognition,[4] the pattern of recognition was specific to a small percentage of autoimmune hepatitis type 1 or cryptogenic hepatitis patients.[5]
In
gastric cancer anti-actin antibodies were elevated, along with other antibodies in severe disease with poor outcomes.[6]
It has also been found as a paraneoplastic syndrome with myelodysplastic syndrome.[7]