Antibiotic prophylaxis
Antibiotic prophylaxis refers to, for humans, the
For humans
Antibiotic prophylaxis is most commonly used prior to
Even when
Antibiotic prophylaxis is also commonly used to prevent respiratory tract infections in antibody deficient patients.[5]
Local wound infections (superficial or deep-sided),
Worldwide experience with antimicrobial prophylaxis in surgery has proven to be effective and cost-efficient, both avoiding severe patient suffering while saving lives (provided the appropriate antibiotics have been carefully chosen and used to the best of current medical knowledge).[citation needed]
Antibiotic selection
A proper
For prophylaxis in surgery, only antibiotics with good tolerability should be used.
There are many factors that affect physicians' compliance with guideline recommendations, including cultural factors, educational background, training, nurse and pharmacist influences, medication supply, and logistics.[citation needed]
The American Dental Association (ADA) recommends antibiotic prophylaxis for few people since only a small number of cases of endocarditis might be caused by dental procedures.[9]
Advantages of long-acting antibiotics
Long-acting, broad-spectrum antibiotics offer the following advantages by comparison to short-acting antimicrobials in perioperative prophylaxis:[citation needed]
- A single dose covers the whole perioperative risk period - even if the operation is delayed or long-lasting - and with regard to respiratory and urinary tract infections
- Repeat administrations for prophylaxis are not necessary, so that additional doses are less likely to be forgotten (an advantage of practical value in a busy working situation such as a hospital)
- Less risk of development of resistance and less side effects
- Increased compliance and reduced errors of administration
- Possibly better-effectiveness (less material and labor cost, less septic perioperative complications)
There are many factors that affect physicians' compliance with guideline recommendations, including cultural factors, educational background, training, nurse and pharmacist influences, medication supply, and logistics.[citation needed]
American Heart Association recommendations
The American Heart Association (AHA) now recommends antibiotic prophylaxis for very few patients since only a small number of cases of endocarditis might be prevented by this procedure.[10]
For livestock
Antibiotic prophylaxis in domestic animal feed mixes has been employed in America since at least 1970.[1] Over time, the use of antibiotics for growth promotion purposes in livestock was discovered. In 1986, some European countries banned the use of antibiotics because of research they found that linked antibiotic use in livestock and drug resistant bacteria in humans.[11] The European Union regulated in 2006 against antibiotics for growth promotion purposes.[12]
It was estimated in 2014 that over 80% of the world's antibiotic use was on farms.
Due to the serious problem of superbugs (which are bred in antibiotic-rich environments) the
As of 2016, Health Canada had approved for employment in cattle three natural hormones and three synthetic hormones.[11]
References
- ^ hdl:2142/28536.
- ^ "Antibiotic Prophylaxis". www.ada.org. Retrieved 2022-02-11.
- PMID 28554926.
- ^ "Iv. Antimicrobial Prophylaxis". Archived from the original on 2002-10-18. Retrieved 2005-10-17.
- S2CID 228965989.
- PMID 34849592.
- S2CID 216109202.
- S2CID 42388624.
- ^ "Antibiotic Prophylaxis Prior to Dental Procedures". American Dental Association. 23 March 2020. Retrieved 10 September 2020.
- PMID 17446442.
- ^ a b revivewellness.ca: "Is Canadian Beef Hormone & Antibiotic Free?", April 17, 2016
- ^ a b c d globalnews.ca: "Medicating meat: What's Canada's plan for animal antibiotics?", 08/06/2014
- ^ a b c d cbc.ca: "Health Canada's quiet move to end use of antibiotics to fatten up animals", 09/07/2014
- ^ a b producer.com: "Health Canada tightens antibiotic use", 17/04/2014
- ^ a b ctvnews.ca: "Health Canada restricts use of growth-promoting antibiotics in livestock", 12/07/2014
Further reading
- Glick M (October 2016). "Antibiotics: The good, the bad, and the ugly". J Am Dent Assoc. 147 (10): 771–3. PMID 27688222.