Augmentation (pharmacology)

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Augmentation, in the context of the pharmacological management of psychiatry, refers to the combination of two or more drugs to achieve better treatment results. Examples include:

In pharmacology, the term is occasionally used to describe treatments that increase (augment) the concentration of some substance in the body. This might be done when someone is deficient in a hormone, enzyme, or other endogenous substance. For example:

  • Use of DDCIs in addition to L-DOPA, to reduce conversion of L-DOPA outside the brain.
  • To give α1 antitrypsin to someone with
    alpha 1-antitrypsin deficiency.[4]

References