Global spread of H5N1

Source: Wikipedia, the free encyclopedia.
(Redirected from
Avian flu outbreak of 2009
)

Highly pathogenic H5N1
Highly pathogenic H5N1
Highly pathogenic H5N1
Countries that have reported deaths of poultry or wild birds linked to highly pathogenic H5N1 infection as of March 2023.
Countries that have reported human cases of highly pathogenic H5N1 infection.

The global spread of H5N1

strains are known, they are significantly different on a genetic level from a recent, highly pathogenic, emergent strain of H5N1, which was able to achieve hitherto unprecedented global spread in 2008.[1] The H5N1 strain is a fast-mutating, highly pathogenic avian influenza virus (HPAI) found in multiple bird species. It is both epizootic (an epidemic in non-humans) and panzootic (a disease affecting animals of many species especially over a wide area). Unless otherwise indicated, "H5N1" in this timeline
refers to the recent highly pathogenic strain of H5N1.

Cumulative Human Cases of and Deaths from
H5N1
As of April 11, 2007

Notes:

Tens of millions of birds have died of

H5N1 influenza and hundreds of millions of birds have been slaughtered and disposed of, to limit the spread of H5N1. Countries that have reported one or more major highly pathogenic H5N1 outbreaks in birds (causing at least thousands but in some cases millions of dead birds) are (in order of first outbreak occurrence): South Korea, Vietnam, Japan, Thailand, Cambodia, Laos, Indonesia, China, Malaysia, Russia, Kazakhstan, Mongolia, Turkey, Romania, Croatia, Ukraine, Cyprus, Iraq, Nigeria, Egypt, India, France, Niger, Bosnia, Azerbaijan, Albania, Cameroon, Myanmar, Afghanistan, Israel, Pakistan, Jordan, Burkina Faso, Germany, Sudan, Ivory Coast, Djibouti, Hungary, United Kingdom, Kuwait, Bangladesh, Saudi Arabia, Ghana, Czech Republic, Togo, Nepal, Bhutan, the Philippines, and Chile.[2]

Highly pathogenic H5N1 has been found in birds in the wild in numerous other countries:

H5N1
in humans, poultry, wild birds, cats and other animals remains very weak in many parts of Asia and Africa. Much remains unknown about the exact extent of its spread.

H5N1 has low pathogenic varieties

Influenzavirus A
(bird flu virus).

According to

Robert G. Webster
:

The epicenters of both the

Guangdong Province, China, in 1996, when it killed some geese, but it received little attention until it spread through live-poultry markets in Hong Kong to humans in May 1997, killing 6 of 18 infected people. [...] From 1997 to May 2005, H5N1 viruses were largely confined to Southeast Asia, but after they had infected wild birds in Qinghai Lake, China, they rapidly spread westward. [...] The intermittent spread to humans will continue, and the virus will continue to evolve.Map[4]

On July 25, 2008, the

pathogenicity was continuing to gradually rise in endemic areas but the avian influenza disease situation in farmed birds was being held in check by vaccination. Eleven outbreaks of H5N1 were reported worldwide in June 2008 in five countries (China, Egypt, Indonesia, Pakistan and Vietnam) compared to 65 outbreaks in June 2006 and 55 in June 2007.[5]

Human cases

Country
 Azerbaijan
 Bangladesh
 Cambodia
 Canada
 Chile
 China
 Djibouti
 Ecuador
 Egypt
 India
 Indonesia
 Iraq
 Laos
 Myanmar
 Nepal
 Nigeria
 Pakistan
 Spain
 Thailand
 Turkey
 United Kingdom
 United States
 Vietnam
Total
2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 Total
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
cases
deaths
CFR
8 5 62.5% 8 5 62.5%
1 0 0% 2 0 0% 3 0 0% 1 1 100% 1 0 0% 8 1 12.5%
4 4 100% 2 2 100% 1 1 100% 1 0 0% 1 0 0% 1 1 100% 8 8 100% 3 3 100% 26 14 53.8% 9 4 44.4% 6 4 66.7% 5 1 20.0% 67 42 62.7%
1 1 100% 1 1 100%
1[6] 0 0% 1 0 0%
1 1 100% 8 5 62.5% 13 8 61.5% 5 3 60.0% 4 4 100% 7 4 57.1% 2 1 50.0% 1 1 100% 2 1 50.0% 2 2 100% 2 0 0% 6 1 16.7% 1 1 100% 1 0 0% 55 32 58.2%
1 0 0% 1 0 0%
1 0 0% 1 0 0%
18 10 55.6% 25 9 36.0% 8 4 50.0% 39 4 10.3% 29 13 44.8% 39 15 38.5% 11 5 45.5% 4 3 75.0% 37 14 37.8% 136 39 28.7% 10 3 30.0% 3 1 33.3% 359 120 33.4%
1 1 100% 1 1 100%
20 13 65.0% 55 45 81.8% 42 37 88.1% 24 20 83.3% 21 19 90.5% 9 7 77.8% 12 10 83.3% 9 9 100% 3 3 100% 2 2 100% 2 2 100% 1 1 100% 200 168 84.0%
3 2 66.6% 3 2 66.6%
2 2 100% 1 0 0% 3 2 66.7%
1 0 0% 1 0 0%
1 1 100% 1 1 100%
1 1 100% 1 1 100%
3 1 33.3% 3 1 33.3%
2 0 0% 2 0 0%
17 12 70.6% 5 2 40.0% 3 3 100% 25 17 68.0%
12 4 33.3% 12 4 33.3%
1 0 0% 4 0 0% 5 0 0%
1 0 0% 1 0 0%
3 3 100% 29 20 69.0% 61 19 31.1% 8 5 62.5% 6 5 83.3% 5 5 100% 7 2 28.6% 4 2 50.0% 2 1 50.0% 2 2 100% 1 0 0% 1 1 100% 129 65 50.0%
4 4 100% 46 32 69.6% 98 43 43.9% 115 79 68.7% 88 59 67.0% 44 33 75.0% 73 32 43.8% 48 24 50.0% 62 34 54.8% 32 20 62.5% 39 25 64.1% 52 22 42.3% 145 42 29.0% 10 3 30.0% 4 2 50.0% 0 0 0% 1 1 100% 1 0 0% 2 1 50.0% 6 1 16.7% 12 4 33.3% 6 2 33.3% 888 463 52.1%


Timeline

1959–1997

Ducks play a key role in H5N1 spread

2003

2004

In January 2004 a major new outbreak of

pigeons, and other birds and that it was increasing its ability to infect mammals as well. From this point on, avian influenza
experts increasingly refer to containment as a strategy that can delay but not prevent a future avian flu pandemic.

2005

The spread of avian influenza in the eastern hemisphere.

In January 2005 an outbreak of avian influenza affected thirty three out of sixty four cities and provinces in Vietnam, leading to the forced killing of nearly 1.2 million poultry. Up to 140 million birds are believed to have died or been killed because of the outbreak. In April 2005 there begins an unprecedented die-off of over 6,000 migratory birds at Qinghai Lake in central China over three months. This strain of H5N1 is the same strain as is spread west by migratory birds over at least the next ten months. In August 2005 H5N1 spread to Kazakhstan, Mongolia and Russia. On September 29, 2005, David Nabarro, the newly appointed Senior United Nations System Coordinator for Avian and Human Influenza, warned the world that an outbreak of avian influenza could kill 5 to 150 million people. David Nabarro later stated that as the virus had spread to migratory birds, an outbreak could start in Africa or the Middle East. Later in 2005 H5N1 spread to Turkey, Romania, Croatia and Kuwait.

2006

2007

In January,

.

In March

in May.

As H5N1 continued killing many birds and a few people throughout the spring in countries where it is now endemic, in June

.

In July France and India also saw a resurgence of bird deaths due to H5N1.

2008

January

  • January 24, 2008: China's health ministry has confirmed a 22-year-old man has died from H5N1 in central Hunan province.[19]

February

  • February 26, 2008: H5N1 killed a school teacher from northern Vietnam in the country's 51st death from the disease, and health officials fretted that the virus would spread further.[20]
  • February 28, 2008: There are no indications that H5N1 is becoming a bigger problem in China despite the deaths of three people from the disease this year, the World Health Organisation said Wednesday.[21]

March

  • March 4, 2008: H5N1 virus confirmed as the cause of death for a 25-year-old female from Sennoris District, Fayum Governorate, Egypt.[22]

June

  • June 7, 2008:
    HK$50,000 and six months imprisonment.[25]

July

As of the July 25, 2008

pathogenicity
is continuing to gradually rise in wild birds in endemic areas but the avian influenza disease situation in farmed birds is being held in check by vaccination. Eleven outbreaks of H5N1 were reported worldwide in June 2008 in five countries (China, Egypt, Indonesia, Pakistan and Vietnam) compared to 65 outbreaks in June 2006 and 55 in June 2007. The "global HPAI situation can be said to have improved markedly in the first half of 2008 [but] cases of HPAI are still underestimated and underreported in many countries because of limitations in country disease surveillance systems".
[5]

2009

January

  • January 16, 2009: H5N1 hits Nepal for first time. In a January 16 report to the World Organization for Animal Health (OIE), government officials in Nepal said the virus struck backyard poultry in a village in Jhapa district in the southeastern corner of Nepal.
    Jhapa district. Over 150 chickens died in the Indian border town, 35 km southwest of Kankarbhitta. The Ministry of Agriculture and Cooperatives declared the area surrounding Sharanamati a "bird-flu affected area" and increased surveillance along the border. A Rapid Response Team (RRT) was dispatched to control the virus. The government also banned the transportation of poultry products throughout the country. The first outbreak was confirmed in Kankarbhitta on January 16. 28,000 chickens were killed in the area to control the virus. Earlier, Agriculture Minister Jayprakash Gupta asked the international community and donor agencies to provide help to Nepal fight the disease. The Indo-Nepal border was in heightened alert because of the disease.[27]

February

March

April

  • April 24, 2009: H5N1 virus confirmed as the cause of death for a 23-year-old woman from Thanh Hóa, Vietnam.[32]

June

  • July 1, 2009: Three cases of H5N1 were confirmed in Egypt, all three of whom recovered.[33]

2010

February

2011

June

  • June 16, 2011: Five cases of H5N1 were confirmed in Egypt, three of which were fatal.[36]

December

  • December 20, 2011: Details of research on H5N1 on mutations which enable its transmission to
    NSABB)[37] to be redacted due to concerns over bioterrorism potential.[38]

2012

February

May

2014

January

  • January 3, 2014: An Alberta, Canada resident dies of H5N1 after returning from Beijing, China and feeling unwell on a return flight from Beijing to Vancouver (Air Canada 030) and Vancouver to Edmonton (Air Canada 244)[42] on December 27, 2013 and hospitalized on January 1, 2014;[43] this is the first case in Canada and North America.[44][45]

2022

January

Suidae (pigs)

Pigs can harbor influenza viruses adapted to humans and others that are adapted to birds, allowing the viruses to exchange genes and create a pandemic strain.

Avian influenza virus

H5N1 in pigs.[9]

In 2005, it was discovered that

H5N1 "could be infecting up to half of the pig population in some areas of Indonesia, but without causing symptoms [...] Chairul Nidom, a virologist at Airlangga University's tropical disease center in Surabaya, Java, was conducting independent research earlier this year. He tested the blood of 10 apparently healthy pigs housed near poultry farms in western Java where avian flu had broken out, Nature reported. Five of the pig samples contained the H5N1 virus. The Indonesian government has since found similar results in the same region, Nature reported. Additional tests of 150 pigs outside the area were negative."[48]

Felidae (cats)

Domestic cats can get H5N1 from eating birds, and can transmit it to other cats and possibly to people.

In Bangkok,

H5N1 in 2004. Tigers and leopards in Thai zoos also died, while in 2007 two cats near an outbreak in poultry and people in Iraq were confirmed to have died of H5N1, as were three German cats that ate wild birds. In Austria, cats were infected but remained healthy. Cats in Indonesia were also found to have been infected with H5N1.[49]

The spread to species and populations of birds, and the ability of

H5N1 from eating this natural prey, means the creation of a reservoir for H5N1 in cats where the virus can adapt to mammals is one of the many possible pathways to a pandemic
.

October 2004

Variants have been found in a number of domestic cats,

OIE report reads: "the clinical manifestations began on 11 October 2004 with weakness, lethargy, respiratory distress, and high fever (about 41-42 degrees Celsius). There was no response to any antibiotic treatment. Death occurred within three days following the onset of clinical signs with severe pulmonary lesions."[54]

February 28, 2006

A dead cat infected with the

H5N1 bird flu virus was found in Germany.[55]

March 6, 2006

Hans Seitinger, the top agriculture official in the southern state of Styria, Austria announced that several still living cats in Styria have tested positive for H5N1:[56]

August 2006

It was announced in the August 2006 CDC EID journal that while literature describing HPAI H5N1 infection in cats had been limited to a subset of clade I viruses; a Qinghai-like virus (they are genetically distinct from other clade II viruses) killed up to five cats and 51 chickens from February 3 to 5, 2006 in Grd Jotyar (~10 km north of

Erbil City
, Iraq). Two of the cats were available for examination.

"An influenza A H5 virus was present in multiple organs in all species from the outbreak site in Grd Jotyar (Table). cDNA for sequencing was amplified directly from RNA extracts from pathologic materials without virus isolation. On the basis of sequence analysis of the full HA1 gene and 219 amino acids of the HA2 gene, the viruses from the goose and 1 cat from Grd Jotyar and from the person who died from Sarcapcarn (sequence derived from PCR amplification from first-passage egg material) are >99% identical at the nucleotide and amino acid levels (GenBank nos. DQ435200–02). Thus, no indication of virus adaptation to cats was found. The viruses from Iraq are most closely related to currently circulating Qinghai-like viruses, but when compared with A/bar-headed goose/Qinghai/65/2005 (H5N1) (GenBank no. DQ095622), they share only 97.4% identity at the nucleic acid level with 3 amino acid substitutions of unknown significance. On the other hand, the virus from the cat is only 93.4% identical to A/tiger/Thailand/CU-T4/2004(H5N1) (GenBank no. AY972539). These results are not surprising, given that these strains are representative of different clades (8,9). Sequencing of 1,349 bp of the N gene from cat 1 and the goose (to be submitted to GenBank) show identity at the amino acid level, and that the N genes of viruses infecting the cat and goose are >99% identical to that of A/bar-headed goose/Qinghai/65/2005(H5N1). These findings support the notion that cats may be broadly susceptible to circulating H5N1 viruses and thus may play a role in reassortment, antigenic drift, and transmission."[57]

January 24, 2007

"Chairul Anwar Nidom of

antibodies to H5N1. This does not mean that they were still carrying the virus, only that they had been infected - probably through eating birds that had H5N1. Many other cats that were infected are likely to have died from the resulting illness, so many more than 20% of the original cat populations may have acquired H5N1."[49]

June 26, 2023

On 20 and 21 June in Poland multiple reports of cats dying from unknown causes with neurological and respiratory symptoms that matched H5N1 to some degree. Some viral alerts have risen, mostly posted on Facebook by veterinary clinics alerting their clients. At that time most of the data was anecdotal. [58] On 26 June it was confirmed by Polands Chief Veterinary Officer Paweł Niemczuk, who stated that in 9 of 11 tested cases it is indeed H5N1:

"The results of subsequently tested samples taken from cats from Lublin and Poznań are available. Until June 26 at 11:00 11 samples were tested at the National Veterinary Institute in Puławy, of which 9 gave a positive result for H5N1 influenza. Positive samples come from Poznań, Tri-City, and Lublin. Further detailed studies of the genetic material of viruses are underway. Preliminary research excludes the origin of the influenza virus that has been causing gulls to become ill in recent weeks. Today, a sanitary and epizootic meeting was held, where a plan for further action was discussed."[59]

Mammals in general

Martens
and an unknown number of other mammals can catch H5N1, illustrating the unprecedented ability of H5N1 to survive and spread.

H5N1 has been transmitted in laboratories to many species including mice and ferrets to study its effects. A purposely mutated strain [40] in ferrets[37] has engendered a notable international policy debate regarding the openness of scientific research, the mandates of public health, and the potential for bioterrorism.[60]

H5N1 was transmitted in the wild to three civet cats in Vietnam in August 2005 and a stone marten in Germany in March 2006.[61]

The BBC reported that a stray dog in Azerbaijan died from the disease on March 15, 2006.[62]

People living in areas where the A(H5N1) virus has infected birds are advised to keep their cats indoors. "Cats can be infected through the respiratory tract. Cats can also be infected when they ingest the virus, which is a novel route for influenza transmission in mammals. But cats excrete only one-thousandth the amount of virus that chickens do [...] The concern is that if large numbers of felines and other carnivores become infected, the virus might mutate in a series of events that could lead to an epidemic among humans. Dogs, foxes, seals, and other carnivores may be vulnerable to A(H5N1) virus infection, Dr. Osterhaus said. Tests in Thailand have shown that the virus has infected dogs without causing apparent symptoms."[63]

H5N1 has the potential to infect

bovine species would be a valuable source of additional information about transmission events, especially in regions like Asia and Egypt, where HPAIV (H5N1) is endemic and probability of contact between poultry and cattle is high."[64]

See also

References

  1. ^ "扬子晚报电子版". Archived from the original on October 7, 2008. Retrieved June 12, 2008.
  2. ^ "Chile detects first case of bird flu in a human". Reuters. March 29, 2023. Retrieved March 30, 2023.
  3. ^ "En Uruguay siguen apareciendo casos de gripe aviar". Diario El Comercial (in Spanish). March 15, 2023. Retrieved March 22, 2023.
  4. PMID 17124014
    .
  5. ^ a b "July 25, 2008 FAO Avian Influenza Disease Emergency Situation Update" (PDF). Archived from the original (PDF) on September 9, 2008. Retrieved August 18, 2008.
  6. ^ "Chile detects first case of bird flu in a human". Reuters. March 29, 2023. Retrieved March 30, 2023.
  7. ^ WHO (March 2, 2004). "Situation (poultry) in Asia: need for a long-term response, comparison with previous outbreaks". Disease Outbreak News: Avian Influenza A(H5N1). 31. Archived from the original on March 7, 2004.
  8. PMID 16494709
    .
  9. ^ a b c WHO (October 28, 2005). "H5N1 avian influenza: timeline" (PDF). Archived from the original (PDF) on November 29, 2005.
  10. ^ "香港禽流感大事记". Archived from the original on October 7, 2008. Retrieved June 12, 2008.
  11. PMID 14987888
    .
  12. ^ WHO. "Confirmed Human Cases of Avian Influenza A(H5N1)". Archived from the original on April 23, 2006.
  13. ^ WHO (January 19, 2006). "Confirmed Human Cases of Avian Influenza A(H5N1)". Archived from the original on February 13, 2006.
  14. ^ Branswell, Helen (June 21, 2006). "China had bird flu case two years earlier than Beijing admits: researchers". CBC News.
  15. ^ WHO (February 27, 2003). "Influenza A(H5N1) in Hong Kong Special Administrative Region of China". Disease Outbreak News: Avian Influenza A(H5N1). 2. Archived from the original on August 22, 2003.
  16. ^ WHO. "Chronology of a serial killer". Disease Outbreak News: SARS. 95. Archived from the original on July 9, 2003.
  17. ^ International Institute for Sustainable Development (IISD) (April 14, 2006). "Scientific Seminar on Avian Influenza, the Environment and Migratory Birds". Avian Influenza & Wild Birds Bulletin. 123 (1). Archived from the original on April 27, 2006. Retrieved April 14, 2006.
  18. . Retrieved July 31, 2015.
  19. ^ "China Says 22-Year Old Died of Bird Flu". Voice of America. February 18, 2008. Retrieved February 18, 2008.
  20. ^ "Bird flu kills woman in Vietnam". CNN. February 25, 2008. Archived from the original on February 27, 2008. Retrieved February 26, 2008.
  21. ^ "WHO plays down bird flu threat in China after three human deaths". AFP-Google. February 27, 2008. Retrieved February 28, 2008.
  22. ^ "Avian influenza - situation in Egypt - update 5". WHO. Archived from the original on March 6, 2008.
  23. ^ "Hong Kong finds H5N1 bird flu in poultry market". Reuters. June 7, 2008.
  24. ^ Thestandard.hk. "Thestandard.hk." Business brisk at chicken stalls. Retrieved on July 4, 2008.
  25. ^ Thestandard.hk. "Thestandard.hk." Legal threat in live-chicken battle. Retrieved on July 4, 2008.
  26. ^ CIDRAP article H5N1 hits Nepal for first time, strikes another Indian state published January 20, 2009
  27. ^ Nepal News.Net (2009). "Bird Flu Strikes Nepal". NepalNews.
  28. ^ P. Nam (2009). "Bệnh nhân H5N1 ở Quảng Ninh tử vong". VNExpress. Retrieved April 27, 2009.
  29. ^ "Thêm ca tử vong vì cúm gia cầm" (in Vietnamese). BBC Vietnamese. February 27, 2009. Retrieved April 27, 2009.
  30. ^ Hòa, Thu (2009). "Bệnh nhân 3 tuổi nhiễm H5N1 đã tử vong" (in Vietnamese). Viet Nam Net. Retrieved April 27, 2009.
  31. ^ "Một bệnh nhân tử vong nghi nhiễm cúm gia cầm" (in Vietnamese). Voice of Vietnam. Retrieved April 27, 2009.
  32. ^ VNA (2009). "Bird flu kills Thanh Hoa woman: official". Thanh Niên. Archived from the original on July 9, 2009. Retrieved April 27, 2009.
  33. ^ "WHO | Avian influenza - situation in Egypt - update 20". www.who.int. Archived from the original on July 2, 2009. Retrieved December 1, 2016.
  34. ^ "Immediate notification report" (PDF). Archived (PDF) from the original on May 24, 2013.
  35. ^ "FAO sees signs of decline in H5N1 outbreaks". CIDRAP. Retrieved December 1, 2016.
  36. ^ "Egypt reports 5 H5N1 infections, 3 fatal". CIDRAP. Retrieved December 1, 2016.
  37. ^ a b "NSABB: Studies show how H5N1 can jump natural barrier". CIDRAP. Retrieved December 1, 2016.
  38. ^ "Bird flu: Research row as US raises terror fears". BBC News. December 21, 2011.
  39. ^ "You searched for Govt eats crow on bird flu denial - The Himalayan Times". The Himalayan Times. Retrieved December 1, 2016.
  40. ^ a b "Experts delay call on releasing controversial H5N1 work". BBC News. February 17, 2012.
  41. ^ "Cambodian girl, 10, dies from bird flu: WHO". Google News Article. May 28, 2012.
  42. ^ "Speaking Notes – Deputy Chief Public Health Officer - H5N1 Technical Briefing". Public Health Agency of Canada. January 8, 2014. Retrieved January 21, 2014.
  43. ^ CDCHAN-00360 (January 15, 2014). "Human Infection with Avian Influenza A (H5N1) Virus". CDC. Retrieved January 21, 2014.{{cite web}}: CS1 maint: numeric names: authors list (link)
  44. ^ "First N America H5N1 bird flu death confirmed in Canada". BBC News. January 8, 2014. Retrieved December 1, 2016.
  45. ^ Weisberg, Nicole (January 9, 2014). "WHO releases more details about H5N1 victim". CTV Edmonton. Retrieved January 9, 2014.
  46. ^ "Some 44,000 fowls culled in Bulacan, Pampanga to contain bird flu spread". ABS-CBN News. February 23, 2022. Retrieved February 25, 2023.
  47. ^ "Bird flu detected in 9 provinces in Luzon, 1 in Mindanao". BusinessWorld. October 6, 2022. Retrieved February 25, 2023.
  48. ^ CIDRAP article Indonesian pigs have avian flu virus; bird cases double in China published May 27, 2005
  49. ^ a b New Scientist article Deadly H5N1 may be brewing in cats published January 24, 2007
  50. PMID 16318716
    .
  51. ^ Henry L Niman (October 19, 2004). "Bird Flu May Have Killed Thai Tigers". ProMED mail. Retrieved February 19, 2008.
  52. ^ Henry L Niman (October 22, 2004). "Thailand: Up to 100 Tigers in Sri Racha Zoo Now Affected by Avian Influenza". Retrieved February 19, 2008.
  53. PMID 20669448
    .
  54. ^ Fares Bakhit Naser (April 13, 2006). "Avian Influenza in Jordan: Followup Report No. 2". OIE. Archived from the original on October 13, 2006. Retrieved October 8, 2006.
  55. ^ "German cat gets deadly bird flu". BBC News. February 28, 2006. Retrieved October 8, 2006.
  56. ^ "Austrian Cats Test Positive for Bird Flu". ABC News. March 6, 2006. Archived from the original on October 26, 2006. Retrieved October 8, 2006.
  57. PMID 16972356
    . Authors all part of US Naval Medical Research Unit No. 3, Cairo, Egypt
  58. ^ "Media Reports Of Unusual Cat Deaths In Poland". Avian Flu Diary. June 21, 2023. Retrieved June 28, 2023.
  59. ^ "Poland Vet. Chief: H5N1 Confirmed In Dead Cats Across Several Regions". Avian Flu Diary. June 26, 2023. Retrieved June 28, 2023.
  60. S2CID 178520157
    .
  61. ^ "Bird flu kills Vietnam civet cats". BBC News. August 26, 2005. Retrieved October 7, 2006.
  62. ^ "Bird flu 'causes first dog death'". BBC News. March 15, 2006. Retrieved October 8, 2006.
  63. ^ Lawrence K. Altman (April 6, 2006). "Article on Bird Flu Criticizes Effort to Monitor Cats and Dogs". New York Times. Retrieved October 8, 2006. (Free subscription required to access article.)
  64. PMID 18598640
    .