Zinc finger protein basonuclin-2
(Redirected from
BNC2
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| Location (UCSC) | Chr 9: 16.41 – 16.87 Mb | Chr 4: 84.19 – 84.59 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Zinc finger protein basonuclin-2 is a protein that in humans is encoded by the BNC2 gene.[5][6] BNC2 has recently been shown to influence skin pigmentation levels in Europeans.[7] Genomic region spanning the BNC2 gene has 60% Neanderthal DNA sequence.[8]
See also
- Chromosome 9 (human)
- Zinc finger protein
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000173068 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028487 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 14702039.
- ^ "Entrez Gene: BNC2 basonuclin 2".
- S2CID 6057298.
- PMID 26451479.
Further reading
- Vanhoutteghem A, Djian P (Jan 2007). "The human basonuclin 2 gene has the potential to generate nearly 90,000 mRNA isoforms encoding over 2000 different proteins". Genomics. 89 (1): 44–58. PMID 16942855.
- Vanhoutteghem A, Djian P (Aug 2006). "Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions". Proceedings of the National Academy of Sciences of the United States of America. 103 (33): 12423–8. PMID 16891417.
- Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. PMID 16344560.
- Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG (Jun 2005). "Binding of pRB to the PHD protein RBP2 promotes cellular differentiation". Molecular Cell. 18 (6): 623–35. PMID 15949438.
- Romano RA, Li H, Tummala R, Maul R, Sinha S (May 2004). "Identification of Basonuclin2, a DNA-binding zinc-finger protein expressed in germ tissues and skin keratinocytes". Genomics. 83 (5): 821–33. PMID 15081112.
- Vanhoutteghem A, Djian P (Mar 2004). "Basonuclin 2: an extremely conserved homolog of the zinc finger protein basonuclin". Proceedings of the National Academy of Sciences of the United States of America. 101 (10): 3468–73. PMID 14988505.
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