B type inclusion
B-type inclusions, formerly known as Guarnieri bodies epithelial cells. The absence of Guarnieri bodies cannot be used as to rule out smallpox, however, as more sensitive test need to be performed.
B-type inclusions are the sites of viral replication and are found in all poxvirus-infected cells, unlike A-type inclusions which are more strongly eosinophilic and only found in infections with certain poxviruses.[3]
They are named after the Italian physician Giuseppe Guarnieri.
References
- ^ "Variola Virus". Archived from the original on 23 January 2009. Retrieved 2009-01-02.
- ISBN 1-55581-240-6.
- ISBN 0-8493-6179-6.
Further reading
- GOODPASTURE EW (1959). "Cytoplasmic inclusions resembling Guarnieri bodies, and other phenomena induced by mutants of the virus of fowlpox". Am. J. Pathol. 35 (2): 213–31. PMID 13627123.
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