Balding–Nichols model
Probability density function | |||
Cumulative distribution function | |||
Parameters |
(real) (real) For ease of notation, let , and | ||
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Support | |||
CDF | |||
Mean | |||
Median | no closed form | ||
Mode | |||
Variance | |||
Skewness | |||
MGF | |||
CF |
In population genetics, the Balding–Nichols model is a statistical description of the allele frequencies in the components of a sub-divided population.[1] With background allele frequency p the allele frequencies, in sub-populations separated by Wright's FST F, are distributed according to independent draws from
where B is the Beta distribution. This distribution has mean p and variance Fp(1 – p).[2]
The model is due to
DNA profiles and in population models for genetic epidemiology
.
References
- S2CID 30680826.
- S2CID 8127858. Archived from the original(PDF) on 2008-07-03. Retrieved 2009-02-19.