Barbier–Wieland degradation

Source: Wikipedia, the free encyclopedia.

The Barbier–Wieland degradation is a procedure for shortening the

oxidation to convert the former alpha position into a carboxyl itself.[1][2]

Barbier-Wieland method: going from butanoic acid to propanoic acid

References

  1. ^ Byron Riegel, Byron; Moffett, R. B.; McIntosh A. V. (1955). "nor-Desoxycholic Acid". Organic Syntheses. 24: 38; Collected Volumes, vol. 3, p. 234.
  2. ^ Byron Riegel, Byron; Moffett, R. B.; McIntosh A. V. (1955). "3,12-Diacetoxy-bisnor-cholanyldiphenylethylene". Organic Syntheses. 24: 41; Collected Volumes, vol. 3, p. 237.