Barney S. Graham
Barney S. Graham | |
---|---|
Born | 1953 Kansas City, Missouri |
Spouse(s) | Cynthia Turner-Graham, M.D. |
Children | 3 |
Academic background | |
Education | B.S., biology, Rice University M.D., 1979, University of Kansas School of Medicine Ph.D., Microbiology and Immunology, 1991, Vanderbilt University |
Academic work | |
Institutions | Vaccine Research Center National Institutes of Health Vanderbilt University |
Barney S. Graham is an American immunologist, virologist, and clinical trials physician.
He is currently Professor of Medicine and Microbiology, Biochemistry, & Immunology and Senior Advisor for Global Health Equity[1] at Morehouse School of Medicine in Atlanta. He is the former[2] deputy director of the Vaccine Research Center (VRC), part of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). During his tenure at the VRC, Graham also served as chief of the Viral Pathogenesis Laboratory.
He was elected a member of the National Academy of Sciences in 2022.[3]
Early life and education
Graham was born in Kansas City, Missouri, the first son of Barney Dan Graham, DDS and Carol Ann Hastings and spent most of his childhood in Olathe, Kansas through early high school. The family moved to a farm near Paola, Kansas, where he graduated from Paola High School as valedictorian in 1971. He attended college at Rice University and graduated magna cum laude in 1975 with a BA degree in biology. After earning his medical degree from the University of Kansas School of Medicine in 1979, Graham continued his training at Vanderbilt University where he completed his internship, residency, consecutive chief residencies at Nashville General Hospital and Vanderbilt University Medical Center, followed by infectious diseases fellowship, and a PhD in Microbiology and Immunology.[4]
Career
By 1982, Graham was appointed
Graham was elected a member of the
By 2017, working alongside Jason McLellan, a structural biologist, they discovered that "adding two prolines to a key joint of a vaccine's spike protein could stabilize the structure's prefusion shape" (patent WO2018081318A1). Later, this method would be applied to the COVID-19 vaccine.[14] During the COVID-19 pandemic, Graham's laboratory partnered with Moderna to develop vaccine technology. He was a member of the research team that designed a spike protein to combat the virus.
His research found that some virus proteins change shape after they break into a person's cells, leading to the design of a better vaccine against respiratory syncytial virus.[15][16]
Personal life
Graham is married to Cynthia Turner-Graham, also a physician. She specializes in psychiatry.[17] They have three adult children.
References
- ^ "Barney Graham, MD | Morehouse School of Medicine". www.msm.edu. Retrieved 2023-05-04.
- ^ MacAuley, Sheridan; Fisher, Devin (2021-10-29). "VRC's Graham Retires After More Than 20 Years". NIH Record. Retrieved 2023-05-04.
- ^ "2022 NAS Election".
- ^ "Barney S. Graham, MD'79, PhD 2017: Distinguished Medical Alumnus" (PDF). kumc.info. Archived from the original (PDF) on May 25, 2021. Retrieved January 10, 2021.
- ^ Nashville General Hospital
- ^ a b Wright, Lawrence (December 28, 2020). "The Plague Year". The New Yorker. Retrieved January 10, 2020.
- ^ a b Colmenares, Clinton (2013). "Barney Graham leaves Vanderbilt for NIH, but his feet stay planted". reporter.newsarchive.vumc.org. Retrieved January 10, 2021.
- ^ "First human tests of AIDS vaccine slated". Auburn Journal. August 12, 1987. Retrieved January 10, 2021 – via newspapers.com.
- ^ "New experiment with AIDS vaccines called encouraging". The Sacramento Bee. June 22, 1991. Retrieved January 10, 2021 – via newspapers.com.
- ^ "Barney S. Graham, MD, PhD". the-asci.org. Retrieved January 10, 2021.
- ^ "BARNEY S. GRAHAM, M.D., Ph.D and Theodore C. Pierson, Ph.D." servicetoamericamedals.org. Retrieved January 10, 2021.
- ^ Albany Medical Center Prize 2021
- ^ John J. Carty Award for the Advancement of Science 2022
- ^ Cross, Ryan (September 29, 2020). "The tiny tweak behind COVID-19 vaccines". cen.acs.org. Retrieved January 10, 2021.
- ^ Johnson, Carolyn Y. (December 6, 2020). "A gamble pays off in 'spectacular success': How the leading coronavirus vaccines made it to the finish line". The Washington Post. Retrieved January 10, 2021.
- ^ Allen, Arthur (November 18, 2020). "Government-Funded Scientists Laid the Groundwork for Billion-Dollar Vaccines". khn.org. Retrieved January 10, 2021.
- ^ "CYNTHIA TURNER-GRAHAM, M.D. – DISTINGUISHED PSYCHIATRIST". incirclexec.com. 9 December 2020. Retrieved January 10, 2021.
External links
Barney S. Graham publications indexed by Google Scholar