Ben Feringa

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Ben Feringa
Royal Dutch Shell (1979–1984)
ThesisAsymmetric oxidation of phenols. Atropisomerism and optical activity (1978)
Doctoral advisorHans Wijnberg
Websitebenferinga.com

Bernard Lucas Feringa (Dutch pronunciation:

Molecular Sciences,[3][4] at the Stratingh Institute for Chemistry,[5] University of Groningen, Netherlands, and an Academy Professor of the Royal Netherlands Academy of Arts and Sciences. He was awarded the 2016 Nobel Prize in Chemistry, together with Sir J. Fraser Stoddart and Jean-Pierre Sauvage, "for the design and synthesis of molecular machines".[1][6]

Personal life

Feringa was born as the son of farmer Geert Feringa (1918–1993) and his wife Lies Feringa née Hake (1924–2013). Feringa was the second of ten siblings in a Catholic family. He spent his youth on the family's farm, which is directly on the border with Germany, in Barger-Compascuum in the Bourtange moor. He is of Dutch and German descent. Among his ancestors is the settler Johann Gerhard Bekel. Together with his wife Betty Feringa, he has three daughters. He lives in Paterswolde near Groningen.[7]

Career

Feringa received his

oxidation catalysis, and especially on stereochemistry with major contributions in the field of enantioselective catalysis, including monophos ligand[10] used in asymmetric hydrogenation, asymmetric conjugate additions of organometallic reagents, including the highly reactive organolithium reagents and organic photochemistry and stereochemistry. In the 1990s, Feringa's work in stereochemistry led to major contributions in photochemistry, resulting in the first monodirectional light driven molecular rotary motor[11] and later a molecular car (a so-called nanocar) driven by electrical impulses.[12]

Ben Feringa holds over 30

research papers to date, cited more than 30,000 times and has an h-index in excess of 90.[13] He has guided over 100 PhD students over his career.[14]

Contributions to research

Feringa found that the early introduction of chiroptical molecular switches,

nanorobots powered by molecular motors. Feringa's design and synthesis of nanomolecular machines, specifically molecular switches and molecular motors
, have initiated major novel approaches towards complex and dynamic chemical systems and the dynamic control of function.

Applications of molecular switches developed in his group include responsive materials and

antibiotic resistance, and biofilm formation. Interfacing molecular motors with the macroscopic world by surface assembly on gold nanoparticles[27] and a macroscopic gold film,[28] has shown that the motor functions while chemically bound to a surface, a key result for future nanomachines such as a molecular conveyor belt. Experiments that involve doping liquid crystals with molecular motors demonstrate that the motion of the motor can be harnessed to make macroscopic objects rotate on a liquid crystal film[29] and drive molecular systems out-of-equilibrium. Several of these discoveries were selected for the list of most important chemical discoveries of the year by Chemical & Engineering News
.

In 2011, molecular ‘nanocar’,[12] a molecule that contains molecular motor-based wheels and was shown to move on a solid surface upon subjection to electric current from an STM tip, was highlighted in international daily newspapers & magazines worldwide and selected by the Chinese Academy of Sciences as one of the 10 major discoveries in sciences worldwide.[citation needed] Towards the future discipline of Systems chemistry, the development of a multistage chiral catalysts [30] which comprises an integrated supramolecular system that brings together molecular recognition, chirality transfer, catalysis, stereoelectronic control and enantio-selectivity while all these processes can be enabled or disabled via an internal motor function, moves the design and application of molecular motors to a whole new level of sophistication.

Aside from molecular motors and switches, Feringa's work has crossed many disciplines and includes the use of phosphoramidites as ligands in asymmetric catalysis, an excellent stereocontrol was archived in copper-catalysed C–C bond formation, which led to a breakthrough in catalytic asymmetric conjugate addition.[31] As phosphoramidites found use in industry, recently they utilised them as starting reagents for asymmetric C-P bond formation. Traditionally, an external chiral ligand is used for chiral induction in a C–P coupling reaction, but the competitive coordination of initial and final phosphorus compounds with the metal catalysts, together with an external chiral ligand, reduces the enantioselectivity. As BINOL-containing phosphoramidites have the properties of an intrinsic chiral ligand and simultaneously can serve as a substrate, they hypothesized that they would increase stereoselectivity in C–P coupling processes with aryl compounds, and were delighted when that data confirmed that they did.[32]

Moreover, many other highlighted works are chiral electromagnetic radiation to generate enantioselectivity, low molecular weight gelators, imaging porphyrins with STM, drying induced self-assembly, organic synthesis, CD spectroscopy, asymmetric catalysis, exploring the origins of chirality including the possibility of an extraterrestrial source and various aspects of surface science including surface modification, surface energy control, and porphyrin allayers.

Honours and awards

Feringa at Nobel press conference in Stockholm, Sweden, December 2016

Feringa is a member of many chemical and scientific related societies: In 1998, Feringa was elected as a Fellow of the Royal Society of Chemistry (FRSC). In 2004, he was elected International Honorary Member of the American Academy of Arts and Sciences.[33] Feringa is an elected member, since 2006, and Academy Professor, since 2008, of the Royal Netherlands Academy of Arts and Sciences (KNAW).[34][35] At the KNAW Feringa served as vice-president and Chair of Board of the Science Division.[34] In addition, Feringa is a former president of the Bürgenstock Conference in 2009, Switzerland, and an elected Member of the Academia Europaea since 2010.[36] In 2013, he was appointed as Council Member of the Royal Society of Chemistry. On 13 October 2016, Feringa was elected an Honorary Member of the Royal Netherlands Chemical Society.[37]

In recognition of his contributions to synthetic methodologies and catalysis, Feringa was given the

James Flack Norris Award in Physical Organic Chemistry of the American Chemical Society in 2007, USA, the European Research Council Advanced Grant in 2008, and the Paracelsus Award of the Swiss Chemical Society, in 2008.[40]

Feringa furthermore was awarded the Chirality Medal for distinguished contributions to all aspects of stereochemistry in 2010, the Solvias Ligand Contest Award (shared with John Hartwig, Yale University (US), the Organic Stereochemistry Award in 2011 of the Royal Society of Chemistry, UK, and the Decennial Van‘t Hoff Medal in 2011 of the Genootschap ter Bevordering van de Natuur-, Genees-, en Heelkunde, in the Netherlands.

Feringa's contributions to the molecular sciences have been recognized with the

Arthur C. Cope Scholar Award, the Nagoya Medal of Organic Chemistry,[41] the 2012 Grand Prix Scientifique Cino del Duca,[42]
and the Humboldt award of the Alexander von Humboldt Foundation in 2012, Germany.

In 2013, he won subsequently the Lily European Distinguished Science Award, the Nagoya Gold Medal in Nagoya, Japan, the Yamada-Koga Award in Tokyo, Japan, the Royal Society of Chemistry Award for distinguished service, and the Marie Curie Medal of the Polish Chemical Society.

He has written several invited review articles and book chapters for a number of journals and books including Chemical Reviews, Accounts of Chemical Research, Angewandte and the main textbook in the field of circular dichroism, Comprehensive Chiroptical Spectroscopy.[43]

He won the Theodor Föster Award of the

German Chemical Society (GDCh) & Bunsen-Society for Physical Chemistry in 2014, Germany,[44] and the Arthur C. Cope Late Career Scholars Award of the American Chemical Society in 2015. In November 2015, he was the recipient of the "Chemistry for the future Solvay prize",[45] which was awarded for "his work on groundbreaking research on molecular motors, a research field that paves the way to new therapeutic and technological applications with nanorobots."[45]

On 20 December 2016, Feringa jointly received the Nobel Prize in Chemistry, together with Sir J. Fraser Stoddart and Jean-Pierre Sauvage, for their work on molecular machines.[1] Feringa had been considered a candidate for the Nobel Prize for some time, with The Simpsons including him in a list of candidates in 2010.[46] In 2016, he also received the Hoffman Medal of the German Chemical Society[47] and the Tetrahedron Prize awarded by Elsevier.[48] In 2017, Feringa received the Centenary Prize of the Royal Society of Chemistry.[49] In August 2018, Feringa was awarded the European Gold Medal presented by the European Chemical Society (EuChemS) during the 7th EuChemS Chemistry Congress, held in Liverpool, UK. In 2019, Feringa accepted the Raman Chair of the Indian Academy of Sciences, an honorary position whereby eminent scientists are invited to lecture on their work and interact with the research community in India.[50][51]

In 2008, he was appointed a

Knight of the Order of the Netherlands Lion by Queen Beatrix of the Netherlands,[52] and on 23 November 2016 he was promoted to Commander of the same Order by King Willem-Alexander of the Netherlands.[53] On 1 December 2016 Feringa was made an Honorary Citizen of Groningen.[54] On 6 April 2017 a street in his birthplace Barger-Compascuum was named Prof. Dr. B. L. Feringadam.[55]

In 1997, he completed the 200 km Elfstedentocht in 12 hours.

He was elected a foreign associate of the US National Academy of Sciences in April 2019.[56]

On 2 April 2019, Ben Feringa was conferred an honorary doctoral degree by the University of Johannesburg in recognition of his contributions to the Chemistry field and Scientific community as a whole.[57]

In 2019 he became a member of the

German Academy of Sciences Leopoldina.[58]

He was elected a

Foreign Member of the Royal Society in 2020.[59]

Professional activities

Ben Feringa has served as an editorial board member for several journals published by the

Journal of Organic Chemistry, Journal of the American Chemical Society published by the American Chemical Society
.

On 26 November 2017, Feringa, on a visit to

green card" in China, and will lead a team researching “self-healing materials” at Shanghai’s East China University of Science and Technology.[61]

Feringa is a co-founder of the contract research company Selact (now a part of Kiadis), which was originally established to provide services in the area of organic synthesis but later developed high throughput screening methods.

References

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    Nobelprize.org
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  2. ^ "Bernard Feringa | Biography, Nobel Prize, & Facts | Britannica". 14 May 2023.
  3. ^ "University of Groningen". 7 July 2006.
  4. ^ "University of Groningen". 2 March 2010.
  5. ^ "Stratingh Institute for Chemistry". 17 October 2012.
  6. ^ Chang, Kenneth; Chan, Sewell (5 October 2016). "3 Makers of 'World's Smallest Machines' Awarded Nobel Prize in Chemistry". The New York Times. Retrieved 5 October 2016.
  7. ^ See German and Dutch Wikipedia.
  8. ^ Marianne. "Prof. B.L. (Ben) Feringa". www.nwo.nl. Archived from the original on 5 October 2016. Retrieved 27 May 2017.
  9. ^ Asymmetric oxidation of phenols. Atropisomerism and optical activity. Archived from the original on 6 January 2015. Retrieved 6 January 2015.
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  34. ^ a b "Ben Feringa". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 11 February 2015.
  35. ^ "Laureates Academy Professor Prize and programme". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 8 October 2020.
  36. ^ "Ben L. Feringa". Academia Europaea. Archived from the original on 28 March 2019.
  37. ^ Ben Feringa benoemd tot erelid KNCV – website of the Royal Netherlands Chemical Society
  38. ^ "Prof. dr. B.L. (Ben) Feringa". Netherlands Organisation for Scientific Research. Archived from the original on 4 November 2020.
  39. ^ "Laboratorium für Organische Chemie (LOC)". Archived from the original on 18 December 2014. Retrieved 15 January 2015.
  40. ^ "Paracelsus Prize". Swiss Chemical Society. Archived from the original on 15 January 2015. Retrieved 15 January 2015.
  41. ^ "Nagoya Medal of Organic Chemistry". Archived from the original on 22 April 2019. Retrieved 6 January 2015.
  42. ^ "La Fondation Simone et Cino del Duca". Archived from the original on 8 December 2014. Retrieved 5 January 2015.
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  45. ^ a b "Professor Ben Feringa, Laureate 2015 "Chemistry for the Future Solvay Prize"". Archived from the original on 20 November 2015. Retrieved 5 January 2016.
  46. ^ "Los Simpson predijeron dos premios Nobel hace seis años". El Observador (in Spanish). 14 October 2016.
  47. ^ Ben Feringa awarded August-Wilhelm-von-Hofmann-Denkmünze – website of the Research Center for Functional Molecular Systems (FMS)
  48. ^ Tetrahedron Prize for Creativity in Organic Chemistry – website of Elsevier
  49. ^ Centenary Prize 2017 Winner – website of RSC
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  56. ^ "2019 NAS Election". National Academy of Sciences. 30 April 2019.
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  60. ^ 雷爱侠 (26 October 2017). "诺奖得主Bernard L. Feringa受聘华南师范大学名誉教授". 光明网 (in Chinese (China)). Archived from the original on 27 October 2017. Retrieved 27 October 2017.
  61. ^ "Win a science Nobel and be in the running for a Chinese 'green card'". South China Morning Post. 26 November 2017. Retrieved 3 December 2017.

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