Benralizumab

Source: Wikipedia, the free encyclopedia.
Benralizumab
CD125
Clinical data
Pronunciationben" ra liz' ue mab
Trade namesFasenra
AHFS/Drugs.comMonograph
MedlinePlusa618002
License data
Pregnancy
category
  • AU: B1
Subcutaneous
ATC code
Legal status
Legal status
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6492H10060N1724O2028S42
Molar mass146056.45 g·mol−1
 ☒NcheckY (what is this?)  (verify)

Benralizumab, sold under the brand name Fasenra, is a

CD125). It was developed by MedImmune for the treatment of asthma.[3][4]

Two phase III clinical trials of benralizumab reported meeting their

Common adverse effects include injection site reactions, which were reported in 2.2% of patients (vs. 1.9% for placebo) in clinical trials.[9]

References

  1. ^ "Search Page - Drug and Health Product Register". 23 October 2014.
  2. ^ "Fasenra EPAR". European Medicines Agency (EMA). 17 September 2018. Retrieved 13 October 2020.
  3. USAN Council
    : Benralizumab
  4. PMID 20799138
    .
  5. ^ AstraZeneca's benralizumab reduces asthma exacerbations up to 51% in two late-state studies. Sept 2016
  6. PMID 28530840
    .
  7. ^ "Fasenra (benralizumab) receives US FDA approval for severe eosinophilic asthma". AstraZeneca. 2017-11-14.
  8. ^ "Fasenra granted US Orphan Drug Designation for eosinophilic oesophagitis". www.astrazeneca.com. Retrieved 2019-10-29.
  9. ^ FDA Professional Drug Information

External links

  • "Benralizumab". Drug Information Portal. U.S. National Library of Medicine.