Bentracimab
Intravenous infusion | |
|---|---|
| ATC code |
|
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| PubChem SID | |
| DrugBank | |
| UNII | |
| KEGG | |
| Chemical and physical data | |
| Formula | C2095H3240N560O674S12 |
| Molar mass | 47440.93 g·mol−1 |
Bentracimab is a
clinical trials to function as a reversal agent for the anti–blood clotting drug ticagrelor (which acts as a P2Y12 inhibitor and is sold under the brand name Brilinta among others).[2] It is under investigation for use in major, life-threatening bleeding in patients being treated with ticagrelor.[3][4]
It is not commercially available.
See also
- Other reversal agents for antithrombotic drugs
References
- ^ "Specialist Pharmacy Service: Bentracimab". National Health Service. 10 January 2021.
- ^ "EU patients enrolled in REVERSE-IT trial of bentracimab for reversal of antiplatelet effects of ticagrelor". Cardiovascular News. 2021-01-29.
- ^ Clinical trial number NCT04286438 for "A Phase 3, Multicenter, Open-Label, Single-Arm Study of Bentracimab (PB2452) in Ticagrelor-Treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure (REVERSE-IT Trial)" at ClinicalTrials.gov
- PMID 34028081.
 | This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it. |