Biolex
Biolex Therapeutics was a biotechnology firm in the Research Triangle of North Carolina which was founded in 1997 and raised $190 million from investors. It filed for Chapter 7 bankruptcy on July 5, 2012.[1]
The company focused on expression of difficult-to-synthesize recombinant proteins in its LEX platform, which used have been produced using the LEX platform.
Biolex acquired Epicyte Pharmaceutical Inc. on May 6, 2004, and acquired the LemnaGene SA of Lyon,
thrombolytic. The financial terms of the sale were not disclosed.[7]
References
- ^ Chris Bagley, Staff Writer, for the Triangle Business Journal. July 6, 2012. Biolex Therapeutics files for $38M bankruptcy
- ^ Goodman Peter S. In N.C., A Second Industrial Revolution: Biotech Surge Shows Manufacturing Still Key to U.S. Economy [1] Washington Post Monday, September 3, 2007
- ^ John R. Gasdaska, David Spencer and Lynn Dickey "Advantages of Therapeutic Protein Production in the Aquatic Plant Lemna" BioProcessing Journal, Mar/Apr 2003.
- ^ Cox KM et al. Glycan optimization of a human monoclonal antibody in the aquatic plant Lemna minor. Nat Biotechnol. 2006 Dec; 24(12): 1591-7.
- ^ De Leede LG, Humphries JE, Bechet AC, Van Hoogdalem EJ, Verrijk R, Spencer DG. Novel controlled-release Lemna-derived IFN-alpha2b (Locteron): pharmacokinetics, pharmacodynamics, and tolerability in a phase I clinical trial. J Interferon Cytokine Res. 2008 Feb; 28(2): 113-22.
- ^ Biolex Therapeutics Acquires Lemnagene S.A.
- ^ Biolex Sells LEX System to Synthon and Initiates Sale of Locteron(R) Press Release: Biolex Therapeutics – Mon, May 7, 2012.