Bitot's spots
| Bitot's spots | |
|---|---|
| Other names | ICD10 = E50.1 |
 | |
| Typical location of Bitot's spots | |
| Specialty | Ophthalmology  |
Bitot's spots are the buildup of
Pierre Bitot (1822–1888) first described these spots.[1]
The spots may abate under replacement therapy.[2]
In ancient Egypt, this was treated with animal liver, which is where vitamin A is stored.[3]
Causes
A major cause of Bitot's spots is vitamin A deficiency (VAD).[4] Rarely, pellagra due to deficiency of vitamin B3 (niacin) may also cause Bitot's spots.[5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
Treatment
VAD is commonly treated with oral vitamin A supplements.[6] Improvement of Bitot's spots is seen with high-dose vitamin A therapy.[7] Bitot's spots non-responsive to vitamin A therapy may be removed surgically.[8]
References
- PMID 541036.
- S2CID 52126826.
- ISBN 978-620-0-57824-2.
- PMID 24782581.
- PMID 5315641.
- ^ "Vitamin A Deficiency Treatment & Management: Medical Care, Consultations, Diet". 9 November 2019.
- ^ "Management of Bitot's Spots". American Academy of Ophthalmology. 1 December 2016.
- ^ Themes, U. F. O. (11 September 2016). "Bitot's Spots". Ento Key.
External links
 | This article about the eye is a stub. You can help Wikipedia by expanding it. |