Bouveault aldehyde synthesis

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Bouveault aldehyde synthesis
Named after Louis Bouveault
Reaction type Carbon-carbon bond forming reaction
Identifiers
RSC ontology ID RXNO:0000533

The Bouveault aldehyde synthesis (also known as the Bouveault reaction) is a one-pot

formyl group using a N,N-disubstituted formamide.[1][2]
For primary
formylation reaction, and is named for French scientist Louis Bouveault
.

The Bouveault aldehyde synthesis

Reaction mechanism

The first step of the Bouveault aldehyde synthesis is the formation of the

hydrolyzed
into the desired aldehyde.

Variations

Variants using organolithium reagents instead of magnesium-based Grignard reagents are also considered Bouveault aldehyde syntheses.[3]

See also

References

  1. Bull. Soc. Chim. Fr.
    (in French). 31: 1306–1322.
  2. ^ Louis Bouveault (1904). "Nouvelle méthode générale synthétique de préparation des aldéhydes" [Novel general synthetic method for preparing aldehydes]. Bull. Soc. Chim. Fr. (in French). 31: 1322–1327.