Buphedrone

Source: Wikipedia, the free encyclopedia.
Buphedrone
rectal, buccal
ATC code
  • none
Legal status
Legal status
Pharmacokinetic data
ExcretionUrine
Identifiers
  • 2-(methylamino)-1-phenylbutan-1-one
JSmol)
  • CNC(CC)C(=O)c1ccccc1
  • InChI=1S/C11H15NO/c1-3-10(12-2)11(13)9-7-5-4-6-8-9/h4-8,10,12H,3H2,1-2H3 checkY
  • Key:DDPMGIMJSRUULN-UHFFFAOYSA-N checkY
  (verify)

Buphedrone, also known as α-methylamino-butyrophenone (MABP), is a

chemical classes that was first synthesized in 1928.[1]

Chemistry

Buphedrone is a β-ketone and is related to the naturally occurring compounds

methyl group at the carbon at the α-position relative to the amine
. Another name for buphedrone is phenylacetoethyl-methylamine.

Buphedrone as free base is very unstable; it is prone to dimerization like other α-amino ketones. Because of this, it is sold as various salts, with a hydrochloride being most common.

Effects

Buphedrone increases spontaneous rodent

appetite suppression. It also causes a possibly dangerous effect of decreasing subjective feeling of thirst. The effects of buphedrone have also been compared to methamphetamine
, with more euphoria and less physical stimulation. Most commonly reported effects include:

  • Elevated mood, euphoria
  • Increased alertness
  • Dilated pupils (rare)
  • Slurred speech (rare)
  • Increased heart rate
  • Talkativeness
  • Increased empathy and sense of communication
  • Increased sex drive
  • Temporary erectile dysfunction in men
  • Restlessness
  • Insomnia
  • Increased motivation

Depending on the route of administration, the duration varies from approximately 2.5 (IV) to 6 hours (orally) and may be followed by unpleasant symptoms associated with withdrawal, which may include:

  • Dysphoria
  • Tiredness
  • Sweating
  • Loss of concentration

Legal status

As of October 2015, buphedrone is a controlled substance in China.[2]

Buphedrone is an Anlage II controlled drug in Germany.

In the United States, buphedrone is considered a schedule 1 controlled substance as a positional isomer of mephedrone.[3]

See also

References

  1. doi:10.1021/ja01395a032
    .
  2. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
  3. ^ "Lists of: Scheduling Actions Controlled Substances Regulated Chemicals" (PDF). U.S. Department of Justice. February 2023. Retrieved 7 March 2023.
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