CFU-Meg
| CFU-Meg | |
|---|---|
| Details | |
platelets | |
| Location | Bone marrow |
| Function | Colony forming unit |
| Identifiers | |
| TH | H2.00.04.3.02013 |
| Anatomical terms of microanatomy] | |
CFU-Meg is a colony forming unit. Haematopoiesis in the bone marrow starts off from a haematopoietic stem cell (HSC) and this can differentiate into the myeloid and lymphoid cell lineages. In order to eventually produce a megakaryocyte, the haematopoietic stem cell must generate myeloid cells, so it becomes a common myeloid progenitor, CFU-GEMM. This in turn develops into CFU-Meg, which is the colony forming unit that leads to the production of megakaryocytes.[1][2][3]
Some sources prefer the term "CFU-Mega".[4]
See also
References
- PMID 3124455.
- S2CID 20893511.
- S2CID 9700067.[permanent dead link]
- ISBN 0-7216-0187-1.
External links
- Megakaryocyte+Progenitor+Cells at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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