CPK-MB test
(Redirected from
CK-MB
)| CPK-MB test | |
|---|---|
 Kinetics of cardiac markers in myocardial infarction with or without reperfusion treatment | |
| Reference range | 2 to 19.5 U/L (at 37 C in adults),[1] some places 5 to 25 IU/L[2] |
| LOINC | 49551-5, 51506-4, 2154-3, 13969-1, 32673-6, 38482-6 |
The CPK-MB test (creatine phosphokinase-MB), also known as CK-MB test, is a
phosphocreatine kinase.[citation needed
]
In some locations, the test has been superseded by the
troponin test. However, recently, there have been improvements to the test that involve measuring the ratio of the CK-MB1 and CK-MB2 isoforms.[4]
The newer test detects different
isoenzyme dimers.[citation needed
]
Many cases of CK-MB levels exceeding the blood level of total CK have been reported, especially in newborns with cardiac malformations, especially ventricular septal defects. This reversal of ratios is in favor of pulmonary emboli or vasculitis. An autoimmune reaction creating a complex molecule of CK and IgG should be taken into consideration.[5]
See also
References
- ^ "CREATINE KINASE – MB CK-MB LQ" (PDF).
- PMID 21250193, retrieved 2022-04-18
- PMID 339548.
- ^ "Use of Cardiac Markers in the Emergency Department: - eMedicine". Retrieved 2009-01-10.
- PMID 7090995.