CX-546

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CX-546
Clinical data
Other namesCX-546
Legal status
Legal status
Identifiers
  • 2,3-dihydro-1,4-benzodioxin-7-yl-(1-piperidyl)methanone
JSmol)
  • C1CCN(CC1)C(=O)C2=CC3=C(C=C2)OCCO3
  • InChI=1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2 ☒N
  • Key:LJUNPHMOGNFFOS-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

CX-546 is an

Cortex Pharmaceuticals
.

It has been proposed as a treatment for schizophrenia.[1] CX-546 was the second drug of note to come out of the Cortex research program, after CX-516, but while it was an improvement over its predecessor in some respects, it still has problems with limited oral bioavailability.

However, CX-546 still represented a significant advance that led on to the development of newer compounds such as

barbiturates.[2]

No effective respiratory stimulants are currently marketed for this application, with CX-546 being only the third drug discovered (after

CX-1739 or CX-1763, which are likely to be more suitable for commercial development.[citation needed
]

See also

References

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