Caramiphen

Source: Wikipedia, the free encyclopedia.
Caramiphen
Clinical data
Trade namesCarafen
ATC code
  • None
Identifiers
  • 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate
JSmol)
  • O=C(OCCN(CC)CC)C2(c1ccccc1)CCCC2
  • InChI=1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3
  • Key:OFAIGZWCDGNZGT-UHFFFAOYSA-N

Caramiphen is an

hay fever, and sinusitis.[2] It was added to the British National Formulary in 1963, with a dosage of 10 to 20 mg. Side effects include nausea, dizziness, and drowsiness.[3]

It binds to the sigma-1 receptor with an IC50 value of 25 nM.[4]

References

  1. ^ "Caramiphen". drugs.com. Retrieved 26 September 2012.
  2. ^ "Caramiphen with phenylpropanolamine-oral, Ordrine AT, Rescaps-D, Tuss Vernade, Tusso-Gest". medicine.net. Archived from the original on 29 October 2012. Retrieved 26 September 2012.
  3. PMID 14120813
    .
  4. S2CID 33844132
    .