Carbosulfan
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IUPAC name
2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl [(dibutylamino)sulfanyl]methylcarbamate
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Other names
2,3-Dihydro-2,2-dimethyl-7-benzofuranyl[(dibutylamino)thio] methylcarbamate
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Identifiers | |
3D model (
JSmol ) |
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ChEBI | |
ChemSpider | |
ECHA InfoCard
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100.054.132 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C20H32N2O3S | |
Molar mass | 380.55 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Carbosulfan is an
decomposes slowly at room temperature. Its solubility in water is low but it is miscible with xylene, hexane, chloroform, dichloromethane, methanol and acetone. Carbosulfan is used as an insecticide.[1] The European Union banned use of carbosulfan in 2007.[2]
Its oral
bw, inhalation LC50 is 0.61 mg/L. Carbosulfan is only slightly absorbed through skin (LD50 >2000 mg/kg for rabbits). The mechanism of toxicity is based on reversible inhibition of acetylcholinesterase (as for carbamates generally).[3]
Carbosulfan has very low maximum residue limits for use in the EU and UK examples of this can be seen in apples and oranges, where it is 0.05 mg/kg.
See also
- Carbofuran
- Carbosulfan in the Pesticide Properties DataBase (PPDB)
References
- ^ CARBOSULFAN – Pesticide residues in food – 1984
- ^ COMMISSION DECISION of 13 June 2007 concerning the non-inclusion of carbosulfan in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing that substance
- ^ CARBOSULFAN – Pesticide residues in food – 2003