Cardiovascular physiology
Cardiovascular physiology is the study of the
cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels
("vascular").
These subjects are sometimes addressed separately, under the names cardiac physiology and circulatory physiology.[1]
Although the different aspects of cardiovascular physiology are closely interrelated, the subject is still usually divided into several subtopics.[citation needed]
Heart
- Cardiac output (= heart rate * stroke volume. Can also be calculated with Fick principle, palpating method.)
- Stroke volume (= end-diastolic volume − end-systolic volume)
- Ejection fraction (= stroke volume / end-diastolic volume)
- Cardiac output is mathematically ` to systole[clarification needed]
- Inotropic, chronotropic, and dromotropicstates
- )
- Suction volume (= end-systolic volume + end-diastolic volume)
- Injection fraction(=suction volume / end-systolic volume)
- Cardiac input is mathematically ` to diastole[clarification needed]
- Electrical conduction system of the heart
- Electrocardiogram
- Cardiac marker
- Cardiac action potential
- Frank–Starling law of the heart
- Wiggers diagram
- Pressure volume diagram
Regulation of blood pressure
- Baroreceptor
- Baroreflex
- Renin–angiotensin system
- Juxtaglomerular apparatus
- Aortic body and carotid body
- Autoregulation
- Cerebral Autoregulation
Hemodynamics
Under most circumstances, the body attempts to maintain a steady mean arterial pressure.[2]
When there is a major and immediate decrease (such as that due to
hemorrhage or standing up
), the body can increase the following:
- Heart rate
- arteries)
- Inotropic state
In turn, this can have a significant impact upon several other variables:
- Stroke volume
- Cardiac output
- Pressure
- systolic pressure - diastolic pressure)
- Mean arterial pressure (usually approximated with diastolic pressure + 1/3 pulse pressure)
- Central venous pressure
Regional circulation
| Name of circulation | % of cardiac output | Autoregulation | Perfusion | Comments |
| pulmonary circulation | 100% (deoxygenated) | hypoxia
| ||
| cerebral circulation | 15%[3] | high | under-perfused | Fixed volume means intolerance of high pressure. Minimal ability to use anaerobic respiration |
| coronary circulation | 5% | high | under-perfused | Minimal ability to use systole .)
|
| splanchnic circulation | 15% | low | Flow increases during digestion. | |
hepatic circulation |
15% | Part of portal venous system, so oncotic pressure is very low | ||
| renal circulation | 25% | high | over-perfused | Maintains glomerular filtration rate |
skeletal muscular circulation |
17%[4] | Perfusion increases dramatically during exercise. | ||
cutaneous circulation |
2%[5] | over-perfused | Crucial in thermoregulation. Significant ability to use anaerobic respiration |
See also
References
- ^ Overview Archived January 17, 2007, at the Wayback Machine at Medical College of Georgia
- PMID 25834232.
- ^ Nosek, Thomas M. "Section 3/3ch11/s3c11_13". Essentials of Human Physiology. Archived from the original on 2016-03-24.
- ^ Nosek, Thomas M. "Section 3/3ch11/s3c11_2". Essentials of Human Physiology.[dead link]
- ^ Nosek, Thomas M. "Section 3/3ch11/s3c11_10". Essentials of Human Physiology. Archived from the original on 2016-03-24.
External links
- Cardiovascular+physiology at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Cardiovascular Physiology Concepts - Comprehensive explanation of basic cardiovascular concepts, based on a textbook of the same name.
- The Gross Physiology of the Cardiovascular System - Mechanical overview of cardiovascular function. Free eBook and video resources.
- Clinical Sciences - Cardiovascular An iPhone app covering detailed cardiovascular physiology and anatomy
- Quantitative Cardiovascular Physiology and Clinical Applications for Engineers
| Authority control databases: National |
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