Caroxazone

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Caroxazone
Clinical data
Pregnancy
category
  • ?
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)[1]
  • In general: ℞ (Prescription only)
Identifiers
  • 2-(2-oxo-4H-1,3-benzoxazin-3-yl)acetamide
JSmol)
  • O=C(N)CN2C(=O)Oc1ccccc1C2

Caroxazone (Surodil, Timostenil) is an

MAO-B subtypes, with five-fold preference for the latter.[4][5][6][7][8]

Synthesis

Caroxazone synthesis:[9][10][11][12][13]

Synthesis starts by

NaHCO3
.

See also

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
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  12. ^ GB 1115759, "Carboxamidoalkyl-1,3-benzoxazines", published 1968-05-29, assigned to Societa Farmaceutici Italia 
  13. ^ L. Bernardi et al., U.S. patent 3,427,313 (1969 to Soc. Farma. Italia).