Casokefamide

Casokefamide
Clinical data
Other names	L-tyrosyl-D-alanyl-L-phenylalanyl-D-alanyl-L-tyrosinamide
ATC code	None;
Identifiers
	IUPAC name (2S)-2-[(2R)-2-[(2S)-2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-3-phenylpropanamido]propanamido]-3-(4-hydroxyphenyl)propanamide;
JSmol)	Interactive image;
	SMILES O=C(N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N)Cc1ccc(O)cc1)C)Cc2ccccc2)C)[C@@H](N)Cc3ccc(O)cc3;
	InChI InChI=1S/C33H40N6O7/c1-19(36-32(45)26(34)16-22-8-12-24(40)13-9-22)31(44)39-28(18-21-6-4-3-5-7-21)33(46)37-20(2)30(43)38-27(29(35)42)17-23-10-14-25(41)15-11-23/h3-15,19-20,26-28,40-41H,16-18,34H2,1-2H3,(H2,35,42)(H,36,45)(H,37,46)(H,38,43)(H,39,44)/t19-,20-,26+,27+,28+/m1/s1; Key:XDRHVZLDLNGKLM-FLVVDCEDSA-N;

Casokefamide (

clinical study, casokefamide was found to be effective via the oral route for the treatment of chronic diarrhea, and did not produce any side effects.^[2]

However, further clinical development was not pursued and it was never marketed.

References

^
PMID 8466524
.

^
S2CID 44670226
.

[pmid8466524-1] 
PMID 8466524
.

[pmid10793229-2] 
S2CID 44670226
.

[2]

See also

References